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Title:
APPLICATION OF MONASCINOL IN PREPARATION OF FAT-REDUCING PRODUCT
Document Type and Number:
WIPO Patent Application WO/2021/129166
Kind Code:
A1
Abstract:
An application of monascinol in the preparation of a fat-reducing product. The fat-reducing product comprises a fat-reducing functional food or a fat-reducing drug; the fat-reducing functional food is used for preventing or improving the sub-health status related to obesity of an individual; and the fat-reducing drug is used for preventing or treating diseases related to abnormal lipid metabolism of an individual. Monascinol has new functions of significantly reducing blood lipids, controlling weight gain and inhibiting body fat accumulation; in addition, same has reduced cytotoxicity and has higher usage safety as a fat-reducing product.

Inventors:
CHEN MIANHUA (CN)
WANG LU (CN)
ZHANG YAN (CN)
WANG XIAOLU (CN)
WANG YURONG (CN)
Application Number:
PCT/CN2020/126114
Publication Date:
July 01, 2021
Filing Date:
November 03, 2020
Export Citation:
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Assignee:
TIANJIN UNIV OF SCIENCE AND TECHNOLOGY (CN)
International Classes:
A23L33/10; A61K31/352; A61P3/04
Foreign References:
CN110898053A2020-03-24
CN111304093A2020-06-19
TW201100435A2011-01-01
CN101862327A2010-10-20
Other References:
LI XUEMEI, LIU CHUNLI, DUAN ZHENWEN, GUO SHUREN: "HMG-CoA Reductase Inhibitors from Monascus -Fermented Rice", JOURNAL OF CHEMISTRY, vol. 2013, 1 January 2013 (2013-01-01), US, pages 1 - 6, XP055823833, ISSN: 2090-9063, DOI: 10.1155/2013/872056
LEE, C. L. ET AL.: "Monascin and Ankaflavin Act as Novel Hypolipidemic and High-Density Lipoprotein Cholesterol-Raising Agents in Red Mold Dioscorea", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 58, no. 16, 28 July 2010 (2010-07-28), pages 9013 - 9019, XP002667414
WU, WEI ET AL.: "Relation between Baseline Lipid Levels and Effectiveness of HMG-CoA Reductase Inhibitors in Patients with Hyperlipidemia", SOUTH CHINA JOURNAL OF CARDIOLOGY, vol. 7, no. 2, 30 April 2001 (2001-04-30), pages 110 - 113, XP055824062
QU, JINGWEI ET AL.: "HMG-CoA Reductase Inhibitors: A New Class Of Lipid Lowering Drugs", CHINESE PHARMACOLOGICAL BULLETIN, vol. 6, no. 5, 31 December 1990 (1990-12-31), pages 316, XP055824064
JIA, SHICHEN ET AL.: "Advances of New Functional Ingredients and Efficacy on Monascus Fermented Products", CHINA FOOD ADDITIVES, no. 4, 31 December 2015 (2015-12-31), pages 179 - 184, XP055824067
Attorney, Agent or Firm:
LEADER PATENT & TRADEMARK FIRM (CN)
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