Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
APPLICATION OF NADH AND SALT AND/OR NMN THEREOF IN PREPARATION OF DRUG OR HEALTH CARE PRODUCT FOR ENHANCING MUSCLE OR INHIBITING MUSCLE VOLUME REDUCTION
Document Type and Number:
WIPO Patent Application WO/2021/068802
Kind Code:
A1
Abstract:
Provided is an application of NADH and a salt and/or NMN thereof in the preparation of a drug or health care product for enhancing muscle or inhibiting muscle volume reduction. Provided is a drug composition or health care product composition for enhancing muscle or inhibiting muscle volume reduction, containing NADH and a salt and/or NMN thereof, and containing no active ingredients other than NADH and salts and/or NMN thereof. The NADH and salts and/or NMN thereof may be administered enterally or parenterally, and the routes of administration are broad and convenient. The invention is suitable for persons having insufficient exercise and middle-aged and elderly persons, and according to the severity of the disease condition, the drug administration route and dosage are adjusted.

Inventors:
CHEN JIANSHENG (CN)
ZHANG BO (CN)
Application Number:
PCT/CN2020/118812
Publication Date:
April 15, 2021
Filing Date:
September 29, 2020
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
HOBOOMLIFE BIO TECH SHENZHEN CO LTD (CN)
International Classes:
A61K31/7084; A23L33/00; A61K31/706; A61P21/00
Domestic Patent References:
WO2019141627A12019-07-25
WO2018112541A12018-06-28
Foreign References:
CN110638826A2020-01-03
CN110237089A2019-09-17
CN104352513A2015-02-18
CN108135955A2018-06-08
Other References:
NEELAKANTAN HARSHINI; BRIGHTWELL CAMILLE R.; GRABER TED G.; MAROTO ROSARIO; WANG HUA-YU LEO; MCHARDY STANTON F.; PAPACONSTANTINOU : "Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle", BIOCHEMICAL PHARMACOLOGY, ELSEVIER, US, vol. 163, 1 January 1900 (1900-01-01), US, pages 481 - 492, XP085659298, ISSN: 0006-2952, DOI: 10.1016/j.bcp.2019.02.008
ZHU KEQING, SWANSON RAYMOND A, YING WEIHAI: "NADH Can Enter into Astrocytes and Block Poly(ADP-ribose) Polymerase-1-Mediated Astrocyte Death.", NEUROREPORT., vol. 16, no. 11, 1 August 2005 (2005-08-01), pages 1209 - 1212, XP009527261, DOI: 10.1097/00001756-200508010-00015
MILLS KATHRYN F.; YOSHIDA SHOHEI; STEIN LIANA R.; GROZIO ALESSIA; KUBOTA SHUNSUKE; SASAKI YO; REDPATH PHILIP; MIGAUD MARIE E.; APT: "Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice", CELL METABOLISM, CELL PRESS, UNITED STATES, vol. 24, no. 6, 27 October 2016 (2016-10-27), United States, pages 795 - 806, XP029847468, ISSN: 1550-4131, DOI: 10.1016/j.cmet.2016.09.013
Attorney, Agent or Firm:
SHENZHEN CIPRUN INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
Download PDF: