Title:
AROG ALDOLASE VARIANT AND METHOD FOR PRODUCING BRACHED CHAIN AMINO ACID BY USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/163981
Kind Code:
A1
Abstract:
The present application relates to a phospho-2-dehydro-3-deoxyheptonate (aroG) aldolase variant, a microorganism comprising same, and a method for producing an amino acid by using same.
Inventors:
LEE HAYUN (KR)
KIM JU EUN (KR)
LEE JI HYE (KR)
LEE HEESEOK (KR)
KIM KYUNGRIM (KR)
KIM JU EUN (KR)
LEE JI HYE (KR)
LEE HEESEOK (KR)
KIM KYUNGRIM (KR)
Application Number:
PCT/KR2021/016966
Publication Date:
August 04, 2022
Filing Date:
November 18, 2021
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12N9/10; C12N15/77; C12P13/06; C12P13/08
Foreign References:
| JP3185261B2 | 2001-07-09 | |||
| JP3225597B2 | 2001-11-05 | |||
| EP2147972A1 | 2010-01-27 | |||
| KR20030048140A | 2003-06-18 | |||
| US9109242B2 | 2015-08-18 | |||
| US7662943B2 | 2010-02-16 | |||
| US10584338B2 | 2020-03-10 | |||
| US10273491B2 | 2019-04-30 | |||
| KR20200136813A | 2020-12-08 | |||
| KR102143964B1 | 2020-08-12 | |||
| US20200340022A1 | 2020-10-29 | |||
| US8465962B2 | 2013-06-18 | |||
| KR100057684A | ||||
| KR20180077008A | 2018-07-06 |
Other References:
DATABASE Protein GenPept; ANONYMOUS : "3-deoxy-7-phosphoheptulonate synthase class II [Corynebacterium glutam]", XP055953530, retrieved from NCBI
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
RICE ET AL., TRENDS GENET., vol. 16, 2000, pages 276 - 277
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
SCHWARTZDAYHOFF: "Atlas of Protein Sequence and Structure", NATIONAL BIOMEDICAL RESEARCH FOUNDATION, 1979, pages 353 - 358
J. SAMBROOK ET AL.: "Molecular Cloning", 1989, COLD SPRING HARBOR LABORATORY PRESS
SITNICKA ET AL.: "Functional Analysis of Genes.", ADVANCES IN CELL BIOLOGY. 2010, vol. 2, pages 50 - 51,7-8
SAMBROOK ET AL., MOLECULAR CLONING, 2012
NAKASHIMA N ET AL.: "Bacterial cellular engineering by genome editing and gene silencing.", INT J MOL SCI., vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS - TRENDS IN GENETICS, vol. 1, no. 1, 1986
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
RICE ET AL., TRENDS GENET., vol. 16, 2000, pages 276 - 277
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
SCHWARTZDAYHOFF: "Atlas of Protein Sequence and Structure", NATIONAL BIOMEDICAL RESEARCH FOUNDATION, 1979, pages 353 - 358
J. SAMBROOK ET AL.: "Molecular Cloning", 1989, COLD SPRING HARBOR LABORATORY PRESS
SITNICKA ET AL.: "Functional Analysis of Genes.", ADVANCES IN CELL BIOLOGY. 2010, vol. 2, pages 50 - 51,7-8
SAMBROOK ET AL., MOLECULAR CLONING, 2012
NAKASHIMA N ET AL.: "Bacterial cellular engineering by genome editing and gene silencing.", INT J MOL SCI., vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS - TRENDS IN GENETICS, vol. 1, no. 1, 1986
Attorney, Agent or Firm:
HANOL INTELLECTUAL PROPERTY AND LAW (KR)
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