Title:
AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/192602
Kind Code:
A1
Abstract:
The present invention relates to an aromatic compound and a preparation method therefor and the use thereof. Specifically, disclosed are a compound as shown in the following general formula (I), or a tautomer, an enantiomer, a diastereomer or a racemate thereof or a mixture thereof, or a pharmaceutically acceptable salt thereof. Also disclosed are a method for preparing the above compound and the use of same in the treatment of nervous system diseases.
Inventors:
XUE TAO (CN)
HUANG JING (CN)
WANG WENKE (CN)
CHEN YILANG (CN)
HUANG JING (CN)
WANG WENKE (CN)
CHEN YILANG (CN)
Application Number:
PCT/CN2019/081533
Publication Date:
October 10, 2019
Filing Date:
April 04, 2019
Export Citation:
Assignee:
SHANGHAI JIANHE PHARMACEUTICAL & TECH CO LTD (CN)
International Classes:
C07D295/155; A61K31/122; A61K31/133; A61P25/00; A61P25/04; A61P25/28; C07C225/20; C07C237/02; C07D295/145
Domestic Patent References:
| WO2018104729A1 | 2018-06-14 | |||
| WO2017087388A1 | 2017-05-26 |
Foreign References:
| CN104395283A | 2015-03-04 |
Other References:
MORRIS P.J.: "Synthesis and N-Methyl-D-aspartate (NMDA) Receptor Activity of Ketamine Metabolites", ORG. LETT., vol. 19, 22 August 2017 (2017-08-22), XP055410503, ISSN: 1523-7060
ARCH GEN PSYCHIATRY, vol. 63, no. 8, 2006, pages 856 - 864
ZANOS ET AL., NATURE, vol. 533, May 2016 (2016-05-01), pages 481 - 486
See also references of EP 3778579A4
ARCH GEN PSYCHIATRY, vol. 63, no. 8, 2006, pages 856 - 864
ZANOS ET AL., NATURE, vol. 533, May 2016 (2016-05-01), pages 481 - 486
See also references of EP 3778579A4
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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