Title:
AROMATIC HETEROCYCLIC COMPOUND HAVING TRICYCLIC STRUCTURE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/047553
Kind Code:
A1
Abstract:
An aromatic heterocyclic compound having a tricyclic structure, and a preparation method therefor and application thereof, and in particular, a compound as shown in formula I, or an optical isomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof. The compound shown in formula I may be used to treat diseases associated with a PD-1/PD-L1 signaling pathway.
Inventors:
WANG ZHE (CN)
BAI HAIYUN (CN)
LI DELIANG (CN)
QIAN ANRAN (CN)
BAI HAIYUN (CN)
LI DELIANG (CN)
QIAN ANRAN (CN)
Application Number:
PCT/CN2020/114261
Publication Date:
March 18, 2021
Filing Date:
September 09, 2020
Export Citation:
Assignee:
SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO LTD (CN)
International Classes:
C07D413/14; A61K31/4439; A61K31/4545; A61P35/00; A61P37/02; C07D405/14; C07D409/14; C07D487/10
Domestic Patent References:
| WO2018195321A1 | 2018-10-25 | |||
| WO2019023575A1 | 2019-01-31 | |||
| WO2019169123A1 | 2019-09-06 | |||
| WO2012158550A2 | 2012-11-22 | |||
| WO2018195321A1 | 2018-10-25 | |||
| WO2017059135A1 | 2017-04-06 |
Foreign References:
| CN109803651A | 2019-05-24 | |||
| CN109665968A | 2019-04-23 | |||
| CN110092745A | 2019-08-06 |
Other References:
ORGANIC LETTERS, vol. 21, 2019, pages 5971 - 5976
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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