Title:
ASK1 INHIBITING AGENTS
Document Type and Number:
WIPO Patent Application WO/2020/006031
Kind Code:
A8
Abstract:
Provided are compounds of Formula (I): including compounds of Formulas (II), (III) and (IV), wherein X, R1, R2, R3 and n are as defined herein, and pharmaceutically acceptable salts thereof, and methods for their use and production. These compounds can be useful, e.g., in the treatment of disorders responsive to the inhibition of apoptosis signal-regulating kinase 1 (ASK1).
Inventors:
GONZALEZ LOPEZ DE TURISO FELIX (US)
DECHANTSREITER MICHAEL (US)
XIN ZHILI (US)
JONES JOHN (US)
HIMMELBAUER MARTIN (US)
DECHANTSREITER MICHAEL (US)
XIN ZHILI (US)
JONES JOHN (US)
HIMMELBAUER MARTIN (US)
Application Number:
PCT/US2019/039156
Publication Date:
September 24, 2020
Filing Date:
June 26, 2019
Export Citation:
Assignee:
BIOGEN MA INC (US)
International Classes:
C07D401/14; A61K31/444; A61P25/28
Attorney, Agent or Firm:
DAVIS, Steven, G. et al. (US)
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