Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
AZA SEVEN-MEMBERED RING INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/098859
Kind Code:
A1
Abstract:
An aza seven-membered ring inhibitor, and a preparation method therefor and use thereof. Specifically, a compound has a structure represented by formula (I). Disclosed are a preparation method for the compound and the use of same as a KRASG12C inhibitor. The compound has a good selective inhibition effect on KRASG12C, and has better pharmacodynamic and pharmacokinetic performance, and lower toxic and side effects.

More Like This:
JPS6293259TRICYCLIC COMPOUND AND DETERMINATION FOR ANTIDEPRESSANT
WO/2007/035143STABILIZED PROTEASE COMPOSITION
WO/2001/025212CYCLIC BIPHENYLS, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS MEDICAMENTS
Inventors:
LV BINHUA (CN)
CUI DAWEI (CN)
LIU LIANJUN (CN)
Application Number:
PCT/CN2020/130641
Publication Date:
May 27, 2021
Filing Date:
November 20, 2020
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SUZHOU ZELGEN BIOPHARMACEUTICALS CO LTD (CN)
SHANGHAI ZELGEN PHARMA TECH CO LTD (CN)
International Classes:
C07D223/00; A61K31/445; A61P35/00; C07D239/00; C07D487/02; C07D487/04
Domestic Patent References:
WO2020047192A12020-03-05
WO2019099524A12019-05-23
Foreign References:
CN109843856A2019-06-04
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: RESOURCE PRE-EMPTION SIDELINK COMMUNICATION

Next Patent: APPARATUS AND METHOD OF WIRELESS COMMUNICATION