Title:
BARRIER FUNCTION IMPROVER
Document Type and Number:
WIPO Patent Application WO/2022/168846
Kind Code:
A1
Abstract:
A barrier function improver which contains methylhesperidin as an active ingredient, and a barrier function improver composition which contains said barrier function improver and a pharmaceutically acceptable carrier.
Inventors:
NAKAGAMI YUKO (JP)
Application Number:
PCT/JP2022/003962
Publication Date:
August 11, 2022
Filing Date:
February 02, 2022
Export Citation:
Assignee:
SHOWA DENKO KK (JP)
International Classes:
A61K31/7034; A61K8/60; A61K31/7048; A61P17/16; A61Q19/00; C07H15/203; C07H17/07
Domestic Patent References:
| WO2016076310A1 | 2016-05-19 |
Foreign References:
| JP2011105714A | 2011-06-02 | |||
| US20140086977A1 | 2014-03-27 | |||
| JP2014114290A | 2014-06-26 | |||
| JP2007091693A | 2007-04-12 | |||
| JP2021016111A | 2021-02-12 | |||
| JP2011032191A | 2011-02-17 | |||
| JP6312333B2 | 2018-04-18 |
Other References:
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YI RUOKUN, TIAN YU, TAN FANG, LI WENFENG, MU JIANFEI, LONG XINGYAO, PAN YANNI, ZHAO XIN: "Intervention effect of Malus pumila leaf flavonoids on senna‐induced acute diarrhea in BALB/c mice", FOOD SCIENCE & NUTRITION, vol. 8, no. 5, 1 May 2020 (2020-05-01), pages 2535 - 2542, XP055955887, ISSN: 2048-7177, DOI: 10.1002/fsn3.1549
MINA YAA ET AL.: "Retinoic Acid Delays the Terminal Differentiation of Keratinocytes in Suspension Culture.", J INVEST DERMATOL, vol. 76, 1981, pages 363 - 366, XP009082967, DOI: 10.1111/1523-1747.ep12520026
AKEMI ISHIDA-YAMAMOTO ET AL.: "Structural organization of cornified cell envelopes and alterations in inherited skin disorders.", EXP DERMATOL, vol. 7, 1998, pages 1 - 10, XP071774926, DOI: 10.1111/j.1600-0625.1998.tb00295.x
KAYOKO AKIMOTO ET AL.: "Quantitative Analysis of Stratum Corneum Lipids in Xerosis and Asteatotic Eczema.", THE JOURNAL OF DERMATOLOGY, vol. 20, 1993, pages 1 - 6
GENJI LMOKAWA ET AL.: "Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin?", J INVEST DERMATOL, vol. 96, 1991, pages 523 - 526, XP009061943, DOI: 10.1111/1523-1747.ep12470233
TOKUJI SEGUCHI ET AL.: "Decreased expression of filaggrin in atopic skin.", ARCH DERMATOL RES, vol. 288, 1996, pages 442 - 446, XP002950708, DOI: 10.1007/s004030050080
HIROSHI FUJITA ET AL.: "Palo Azul Prevents Dryness-Induced Decrease in Filaggrin and Amino Acids", J. SOC. COSMET. CHEM. JPN., vol. 37, no. 2, 2003, pages 84 - 91
MARIKO HARA-CHIKUMA ET AL.: "Aquaporin-3 functions as a glycerol transporter in mammalian skin. Biol.", CELL, vol. 97, 2005, pages 479 - 486
TAKUO YUKI ET AL.: "Tight junction proteins in keratinocytes: localization and contribution to barrier function.", EXPERIMENTAL DERMATOLOGY, vol. 16, 2007, pages 324 - 330, XP055657368, DOI: 10.1111/j.1600-0625.2006.00539.x
SAKIEKI, NIPPON KAGAKU ZASSI, vol. 79, 1958, pages 733 - 736
"Japanese Pharmaceutical Codex, Japanese Pharmaceutical Excipients", 2013, YAKUJI NIPPO, LTD., article "Japanese Pharmacopoeia"
"Japanese Pharmaceutical Excipients Directory", 2016, YAKUJI NIPPO, LTD.
"Handbook of Pharmaceutical Excipients", 2012, PHARMACEUTICAL PRESS
"Science Society of Japan", 1984, YAKUJI NIPPO, LTD., article "Japanese Standards of Cosmetic Ingredients"
"Comprehensive Licensing Standards of Cosmetics by Category", 1993, YAKUJI NIPPO, LTD.
"Dictionary of Cosmetic Ingredients", vol. 1-4, 1991, NIKKO CHEMICALS CO., LTD.
"International Cosmetic Ingredient Dictionary and Handbook", 2002
"Pharmaceutical and Medical Device Regulatory Science Society of Japan", 1984, YAKUJI NIPPO, LTD.
YI RUOKUN, TIAN YU, TAN FANG, LI WENFENG, MU JIANFEI, LONG XINGYAO, PAN YANNI, ZHAO XIN: "Intervention effect of Malus pumila leaf flavonoids on senna‐induced acute diarrhea in BALB/c mice", FOOD SCIENCE & NUTRITION, vol. 8, no. 5, 1 May 2020 (2020-05-01), pages 2535 - 2542, XP055955887, ISSN: 2048-7177, DOI: 10.1002/fsn3.1549
MINA YAA ET AL.: "Retinoic Acid Delays the Terminal Differentiation of Keratinocytes in Suspension Culture.", J INVEST DERMATOL, vol. 76, 1981, pages 363 - 366, XP009082967, DOI: 10.1111/1523-1747.ep12520026
AKEMI ISHIDA-YAMAMOTO ET AL.: "Structural organization of cornified cell envelopes and alterations in inherited skin disorders.", EXP DERMATOL, vol. 7, 1998, pages 1 - 10, XP071774926, DOI: 10.1111/j.1600-0625.1998.tb00295.x
KAYOKO AKIMOTO ET AL.: "Quantitative Analysis of Stratum Corneum Lipids in Xerosis and Asteatotic Eczema.", THE JOURNAL OF DERMATOLOGY, vol. 20, 1993, pages 1 - 6
GENJI LMOKAWA ET AL.: "Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin?", J INVEST DERMATOL, vol. 96, 1991, pages 523 - 526, XP009061943, DOI: 10.1111/1523-1747.ep12470233
TOKUJI SEGUCHI ET AL.: "Decreased expression of filaggrin in atopic skin.", ARCH DERMATOL RES, vol. 288, 1996, pages 442 - 446, XP002950708, DOI: 10.1007/s004030050080
HIROSHI FUJITA ET AL.: "Palo Azul Prevents Dryness-Induced Decrease in Filaggrin and Amino Acids", J. SOC. COSMET. CHEM. JPN., vol. 37, no. 2, 2003, pages 84 - 91
MARIKO HARA-CHIKUMA ET AL.: "Aquaporin-3 functions as a glycerol transporter in mammalian skin. Biol.", CELL, vol. 97, 2005, pages 479 - 486
TAKUO YUKI ET AL.: "Tight junction proteins in keratinocytes: localization and contribution to barrier function.", EXPERIMENTAL DERMATOLOGY, vol. 16, 2007, pages 324 - 330, XP055657368, DOI: 10.1111/j.1600-0625.2006.00539.x
SAKIEKI, NIPPON KAGAKU ZASSI, vol. 79, 1958, pages 733 - 736
"Japanese Pharmaceutical Codex, Japanese Pharmaceutical Excipients", 2013, YAKUJI NIPPO, LTD., article "Japanese Pharmacopoeia"
"Japanese Pharmaceutical Excipients Directory", 2016, YAKUJI NIPPO, LTD.
"Handbook of Pharmaceutical Excipients", 2012, PHARMACEUTICAL PRESS
"Science Society of Japan", 1984, YAKUJI NIPPO, LTD., article "Japanese Standards of Cosmetic Ingredients"
"Comprehensive Licensing Standards of Cosmetics by Category", 1993, YAKUJI NIPPO, LTD.
"Dictionary of Cosmetic Ingredients", vol. 1-4, 1991, NIKKO CHEMICALS CO., LTD.
"International Cosmetic Ingredient Dictionary and Handbook", 2002
"Pharmaceutical and Medical Device Regulatory Science Society of Japan", 1984, YAKUJI NIPPO, LTD.
Attorney, Agent or Firm:
OIKAWA Shu et al. (JP)
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