Title:
BENZAZEPINE DERIVATIVES, PREPARATION PROCESS THEREOF AND APPLICATION THEREOF IN MEDICINE
Document Type and Number:
WIPO Patent Application WO/2019/120258
Kind Code:
A8
Abstract:
Provided are a benzazepine derivative, a preparation process thereof and an application thereof in medicine. Specifically, the invention relates to a novel benzazepine derivative represented by formula (I), a process for preparing the same, a pharmaceutical composition containing the same, and an application thereof as a therapeutic agent, particularly as a TLR8 agonist, wherein each substituent of the formula (I) is the same as defined in the specification.
Inventors:
ZHANG GUOBAO (CN)
CHEN YOUXI (CN)
YUAN HUIQING (CN)
HE FENG (CN)
TAO WEIKANG (CN)
CHEN YOUXI (CN)
YUAN HUIQING (CN)
HE FENG (CN)
TAO WEIKANG (CN)
Application Number:
PCT/CN2018/122424
Publication Date:
June 04, 2020
Filing Date:
December 20, 2018
Export Citation:
Assignee:
JIANGSU HENGRUI MEDICINE CO (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D409/02; A61K31/382; A61K31/55; A61P31/00; A61P35/00; C07D223/14; C07D495/00
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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