BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS IDH1 INHIBITORS

Title:

BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS IDH1 INHIBITORS

Document Type and Number:

WIPO Patent Application WO/2020/001474

Kind Code:

A1

Abstract:

The present invention relates to benzimidazole compounds and an application thereof as IDH1 mutant inhibitors, in particular, to a compound as represented by formula (I), tautomers thereof, or pharmaceutically acceptable salts thereof.

More Like This:

WO/2023/222332	DIPHENYL UREAS FOR THE TREATMENT OF VIRAL INFECTIONS
JP7195283	Tinostamstine for use in the treatment of T-cell prolymphocytic leukemia
WO/2007/114213	SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF

Inventors:

WANG DAHAI (CN)
QIAN WENYUAN (CN)
LIU SHILAN (CN)
CHEN SHUHUI (CN)

Application Number:

PCT/CN2019/092997

Publication Date:

January 02, 2020

Filing Date:

June 26, 2019

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MEDSHINE DISCOVERY INC (CN)

International Classes:

A61K31/4184; C07D235/30; A61P35/00

Domestic Patent References:

WO2015121209A1	2015-08-20
WO2017012967A1	2017-01-26
WO2017009325A1	2017-01-19
WO2018071404A1	2018-04-19
WO2018010637A1	2018-01-18
WO2016171756A1	2016-10-27

Foreign References:

CN107848985A	2018-03-27
CN107849059A	2018-03-27
US20170107194A1	2017-04-20
CN107641114A	2018-01-30
CN103958506A	2014-07-30

Other References:

HARTMANN C, ACTA NEUROPATHOL, no. 4, October 2009 (2009-10-01), pages 469 - 74
DANG L, NATURE, vol. 462, no. 7274, 10 December 2009 (2009-12-10), pages 739 - 44
ACTA NEUROPATHOL, vol. 133, 2017, pages 629 - 644

Attorney, Agent or Firm:

SHANGHAI BESHINING LAW OFFICE (CN)

Download PDF:

View/Download PDF PDF Help

Previous Patent: USE OF SMALL NUCLEOLAR RIBONUCLEIC ACID SNORD33 AS BIOMARKER FOR PREPARATION OF DETECTION KIT

Next Patent: PHOSPHORUS-CONTAINING PRODRUGS OF GEMCITABINE