Title:
BENZISOXAZOLE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2022/009863
Kind Code:
A1
Abstract:
The present invention relates to a treatment agent for various diseases of the nervous system and mental illnesses which contains the compound represented in formula (1) or a pharmaceutically acceptable salt thereof as the active component (in the formula, R1 represents a hydrogen, etc., R2 represents a halogen, etc., and R3, R4, R5 and R6 represent a hydrogen, etc.).
Inventors:
TANAKA TOMOYUKI (JP)
ISOBE YOSHIAKI (JP)
KITANO HIROYUKI (JP)
TANAKA HIROAKI (JP)
NARAI SHUN (JP)
ISOBE YOSHIAKI (JP)
KITANO HIROYUKI (JP)
TANAKA HIROAKI (JP)
NARAI SHUN (JP)
Application Number:
PCT/JP2021/025403
Publication Date:
January 13, 2022
Filing Date:
July 06, 2021
Export Citation:
Assignee:
SUMITOMO DAINIPPON PHARMA CO LTD (JP)
International Classes:
A61P1/10; A61K31/423; A61P3/10; A61P9/06; A61P9/12; A61P11/02; A61P15/08; A61P15/10; A61P25/00; A61P25/02; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P29/00; A61P35/00; A61P43/00; C07D261/20
Domestic Patent References:
| WO1994013665A1 | 1994-06-23 | |||
| WO1999033465A1 | 1999-07-08 |
Foreign References:
| JPH037226A | 1991-01-14 | |||
| JPS5377057A | 1978-07-08 | |||
| US4172896A | 1979-10-30 |
Other References:
PERCHALSKI ROBERT J., LEE MIKE S., YOST RICHARD A.: "Biotransformation and Excretion: Metabolite Identification: Other Mass Spectrometric Methods", THE JOURNAL OF CLINICAL PHARMACOLOGY, vol. 26, no. 6, 1 July 1986 (1986-07-01), US , pages 435 - 442, XP093016306, ISSN: 0091-2700, DOI: 10.1002/j.1552-4604.1986.tb03554.x
DATABASE REGISTRY [online] 2014, "Benzofuranmethanesulfonamide, a-(trifluoromethyl)", XP055894686, retrieved from STN Database accession no. 1596612-84-8
SUZUKI, S ET AL.: "Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex", EPILEPSY RESEARCH, vol. 12, no. 1, 1992, pages 21 - 27, XP024394539, DOI: 10.1016/0920-1211(92)90087-A
PHARMACOLOGICAL REVIEWS, vol. 57, no. 4, 2005, pages 397 - 409
DRUG DISCOVERY TODAY, vol. 11, no. 5/6, 2006, pages 245 - 253
"Ion Channels-Advances in Research and Application", 2013, pages: 1 - 106
ACTA UROLOGICA JAPONICA, vol. 57, 2011, pages 125 - 128
JENKINS, RSNYDER, R.L.: "Introduction to X-Ray Powder Diffractometry", 1996, JOHN WILEY & SONS
BUNN, C.W.: "Chemical Crystallography", 1948, CLARENDON PRESS
KLUG, H. P.ALEXANDER, L. E.: "X-Ray Diffraction Procedures", 1974
R. C. LAROCK: "Comprehensive Organic Transformations", 1999, JOHN WILEY & SONS INC.
NEUROBIOLOGY OF DISEASE, vol. 10, 2002, pages 165 - 186
DATABASE REGISTRY [online] 2014, "Benzofuranmethanesulfonamide, a-(trifluoromethyl)", XP055894686, retrieved from STN Database accession no. 1596612-84-8
SUZUKI, S ET AL.: "Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex", EPILEPSY RESEARCH, vol. 12, no. 1, 1992, pages 21 - 27, XP024394539, DOI: 10.1016/0920-1211(92)90087-A
PHARMACOLOGICAL REVIEWS, vol. 57, no. 4, 2005, pages 397 - 409
DRUG DISCOVERY TODAY, vol. 11, no. 5/6, 2006, pages 245 - 253
"Ion Channels-Advances in Research and Application", 2013, pages: 1 - 106
ACTA UROLOGICA JAPONICA, vol. 57, 2011, pages 125 - 128
JENKINS, RSNYDER, R.L.: "Introduction to X-Ray Powder Diffractometry", 1996, JOHN WILEY & SONS
BUNN, C.W.: "Chemical Crystallography", 1948, CLARENDON PRESS
KLUG, H. P.ALEXANDER, L. E.: "X-Ray Diffraction Procedures", 1974
R. C. LAROCK: "Comprehensive Organic Transformations", 1999, JOHN WILEY & SONS INC.
NEUROBIOLOGY OF DISEASE, vol. 10, 2002, pages 165 - 186
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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