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Title:
BERBERINE COMPOSITIONS AND THEIR USE
Document Type and Number:
WIPO Patent Application WO/2021/090214
Kind Code:
A3
Abstract:
The present invention relates to a berberine formulation in solid form, called "sucrosomial® berberine", comprising or, alternatively, consisting of berberine, a lecithin and a first agent selected from a sucrester, a cyclodextrin, a fatty acid and a chitosan derivative, preferably a sucrester. Furthermore, the present invention relates to compositions comprising said sucrosomial® berberine and, optionally, red rice and to the use thereof in the treatment of a condition of dyslipidaemia or impairment of the lipid metabolism, in particular hypercholesterolemia, and/or impairment of the glucose metabolism.

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Inventors:
LACORTE ANDREA (IT)
BRILLI ELISA (IT)
TARANTINO GERMANO (IT)
Application Number:
PCT/IB2020/060383
Publication Date:
June 10, 2021
Filing Date:
November 04, 2020
Export Citation:
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Assignee:
ALESCO SRL (IT)
International Classes:
A61K36/718; A23L33/00; A61K9/107; A61K31/685; A61K31/722; A61K36/29; A61K47/26; A61K47/69; A61P3/04; A61P3/06; A61P3/10
Domestic Patent References:
WO2019038430A12019-02-28
WO2019150225A12019-08-08
WO2017027971A12017-02-23
WO2007113748A12007-10-11
WO1996009814A11996-04-04
Foreign References:
CN106038488B2019-08-23
CN106511260A2017-03-22
EP2149377A12010-02-03
CN1273133C2006-09-06
CN108685870A2018-10-23
CN102525952A2012-07-04
CN1269478C2006-08-16
CN104940167A2015-09-30
CN102793673A2012-11-28
US5993805A1999-11-30
Other References:
DATABASE GNPD [online] MINTEL; 16 February 2018 (2018-02-16), ANONYMOUS: "Cholesterol Control Dietary Supplement", XP055709186, retrieved from www.gnpd.com Database accession no. 5460213
AKHAVAN MAHDAVI SAHAR ET AL: "Microencapsulation optimization of natural anthocyanins with maltodextrin, gum Arabic and gelatin", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, ELSEVIER BV, NL, vol. 85, 6 January 2016 (2016-01-06), pages 379 - 385, XP029412728, ISSN: 0141-8130, DOI: 10.1016/J.IJBIOMAC.2016.01.011
Attorney, Agent or Firm:
HOFFMANN EITLE S.R.L. et al. (IT)
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