Title:
BIARYL COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/047407
Kind Code:
A1
Abstract:
A biaryl compound, a pharmaceutical composition thereof, a preparation method therefor, and a use thereof. The compound has the structure shown in formula I, has a significant regulatory effect on RORγ, can be used as a highly effective RORγ regulator, and has various pharmacological activities such as anti-tumor, anti-autoimmune disease, and anti-inflammatory activities.
Inventors:
LIU JINMING (CN)
TANG JIANCHUAN (CN)
REN YUN (CN)
TIAN QIANG (CN)
SONG HONGMEI (CN)
XUE TONGTONG (CN)
WANG JINGYI (CN)
TANG JIANCHUAN (CN)
REN YUN (CN)
TIAN QIANG (CN)
SONG HONGMEI (CN)
XUE TONGTONG (CN)
WANG JINGYI (CN)
Application Number:
PCT/CN2020/112483
Publication Date:
March 18, 2021
Filing Date:
August 31, 2020
Export Citation:
Assignee:
SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07D231/12; A61K31/538; A61P35/00
Domestic Patent References:
WO2019040842A1 | 2019-02-28 | |||
WO2001081335A1 | 2001-11-01 | |||
WO2012013727A1 | 2012-02-02 |
Foreign References:
CN109568321A | 2019-04-05 | |||
CN105085427A | 2015-11-25 | |||
CN101679266A | 2010-03-24 |
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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