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Title:
BIOLOGICAL TISSUE ADHESIVE SHEET, BIOLOGICAL TISSUE REINFORCING MATERIAL KIT, AND METHOD FOR MANUFACTURING BIOLOGICAL TISSUE ADHESIVE SHEET
Document Type and Number:
WIPO Patent Application WO/2021/054232
Kind Code:
A1
Abstract:
The present invention provides a biological tissue adhesive sheet having exceptional tissue adhesion. A biological tissue adhesive sheet according to an embodiment of the present invention includes a nonwoven fabric formed from fibers that include a crosslinked gelatin derivative, the gelatin derivative being represented by formula 1. Formula 1: Gltn-NH-L-CHR1R2 (In formula 1: Gltn represents a gelatin residue; L represents a single bond or a divalent linking group; and R1 and R2 each independently represent a C1-20 hydrocarbon group or a hydrogen atom, at least one selected from the group consisting of R1 and R2 being the hydrocarbon group.)

Inventors:
TAGUCHI TETSUSHI (JP)
Application Number:
PCT/JP2020/034212
Publication Date:
March 25, 2021
Filing Date:
September 10, 2020
Export Citation:
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Assignee:
NAT INST MATERIALS SCIENCE (JP)
International Classes:
A61L15/32; A61K9/00; A61K45/00; A61K47/42; A61L15/44; A61L15/60; A61L24/00; A61L24/10; A61P31/04; A61P35/00; A61P43/00
Domestic Patent References:
WO2017126390A12017-07-27
WO2014112208A12014-07-24
WO2018079538A12018-05-03
Foreign References:
JP2004321484A2004-11-18
JP2014100420A2014-06-05
JP2000037450A2000-02-08
JP2003301362A2003-10-24
JP2000157622A2000-06-13
Other References:
YAMAOKA, MASATOSHI ET AL.: "Novel Alaska Pollock Gelatin Sealant Shows High Adhesive Quality and Conformability", ANN. THORAC. SURG., vol. 107, June 2019 (2019-06-01), pages 1656 - 1662, XP085694779, ISSN: 0003-4975, DOI: 10.1016/j.athoracsur.2018.11.074
HIROAKI ICHIMARU, YOSUKE MIZUNO, CHEN XI, AKIHIRO NISHIGUCHI, TETSUSHI TAGUCHI: "P67A Development of a hydrophobically modified Alaska pollock-derived gelatin sheet possessing sealing effect for pulmonary air leaks", LECTURE ABSTRACTS OF THE 58TH SYMPOSIUM OF THE ADHESION SOCIETY OF JAPAN; JUNE 18-19, 2020, vol. 58, 18 June 2020 (2020-06-18) - 19 June 2020 (2020-06-19), JP, pages P67A, XP009534700
Attorney, Agent or Firm:
TSUZUKI Noriaki (JP)
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