Title:
BONE CEMENT PASTE CONTAINING AN ANTIBIOTIC
Document Type and Number:
WIPO Patent Application WO1998043685
Kind Code:
A3
Abstract:
The invention relates to an injectable curable bone cement paste based on bioresorbable hydroxyapatite-like compounds comprising calcium phosphate, which contains a cationic antibiotic in the form of a salt, preferably of its sulfate, the curable biodegradable bone cement releasing the antibiotic in biologically active concentrations with depot-like action over a long period of time. The bone cements according to the invention are suitable for the treatment of infectious inflammations of the bone and of the bone marrow, in particular as a result of bone defects and bone fractures.
Inventors:
WENZ ROBERT (DE)
NIES BERTHOLD (DE)
NIES BERTHOLD (DE)
Application Number:
PCT/EP1998/001546
Publication Date:
January 07, 1999
Filing Date:
March 17, 1998
Export Citation:
Assignee:
MERCK PATENT GMBH (DE)
WENZ ROBERT (DE)
NIES BERTHOLD (DE)
WENZ ROBERT (DE)
NIES BERTHOLD (DE)
International Classes:
A61L24/00; A61L24/02; A61L27/12; A61L27/54; A61F2/00; (IPC1-7): A61L25/00
Foreign References:
| US4291013A | 1981-09-22 | |||
| EP0147021A1 | 1985-07-03 | |||
| EP0242672A2 | 1987-10-28 |
Download PDF: