Title:
BORNEOL-BASED POLYMER, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/135550
Kind Code:
A1
Abstract:
A borneol-based polymer, preparation method therefor, and application thereof, belonging to the technical field of polymer chemistry. The polymer has dextrorotated borneol and diethylene glycol monovinyl ether as ingredients, and p-toluenesulfonic acid as a catalyst; substitution and an etherification reaction are performed, and a borneol-based polymer having a uniquely advantageous antibacterial effect is obtained. ε-caprolactone is further added with same as ingredients, polymerization is performed by means of stannous octoate catalysis, and a borneol-based polymer having acid degradation characteristics is obtained, and which can be used to prepare an anti-tumor drug. The materials used in the present invention are simple and easy to obtain, the reaction conditions are mild, and the operations required are straightforward, such that said invention possesses broad application prospects.
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Inventors:
SU JIANYU (CN)
YANG LIU (CN)
FANG LIMING (CN)
MENG XIAOFENG (CN)
YANG LIU (CN)
FANG LIMING (CN)
MENG XIAOFENG (CN)
Application Number:
PCT/CN2020/123223
Publication Date:
July 08, 2021
Filing Date:
October 23, 2020
Export Citation:
Assignee:
UNIV SOUTH CHINA TECH (CN)
International Classes:
C08G67/00; A61K31/765; A61P35/00; C08G63/664; C08G65/00
Foreign References:
| CN103881010A | 2014-06-25 | |||
| CN108863734A | 2018-11-23 | |||
| CN105147647A | 2015-12-16 |
Other References:
ROTH STEFFEN, FUNK IRINA, HOFER MICHAEL, SIEBER VOLKER: "Chemoenzymatic Synthesis of a Novel Borneol-Based Polyester", CHEMSUSCHEM, WILEY-VCH, DE, vol. 10, no. 18, 22 September 2017 (2017-09-22), DE, pages 3574 - 3580, XP055826074, ISSN: 1864-5631, DOI: 10.1002/cssc.201701146
LUO LINGQIONG, LI GUOFENG, LUAN DI, YUAN QIPENG, WEI YEN, WANG XING: "Antibacterial Adhesion of Borneol-Based Polymer via Surface Chiral Stereochemistry", APPLIED MATERIALS & INTERFACES, AMERICAN CHEMICAL SOCIETY, US, vol. 6, no. 21, 12 November 2014 (2014-11-12), US, pages 19371 - 19377, XP055826075, ISSN: 1944-8244, DOI: 10.1021/am505481q
LUO LINGQIONG, LI GUOFENG, LUAN DI, YUAN QIPENG, WEI YEN, WANG XING: "Antibacterial Adhesion of Borneol-Based Polymer via Surface Chiral Stereochemistry", APPLIED MATERIALS & INTERFACES, AMERICAN CHEMICAL SOCIETY, US, vol. 6, no. 21, 12 November 2014 (2014-11-12), US, pages 19371 - 19377, XP055826075, ISSN: 1944-8244, DOI: 10.1021/am505481q
Attorney, Agent or Firm:
GUANGZHOU HUAXUE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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