Title:
BRAIN-TARGETED NASAL DRUG DELIVERY DEVICE AND BODY POSITION FIXATOR THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/127857
Kind Code:
A1
Abstract:
Provided are a brain-targeted nasal drug delivery device and a body position fixator thereof. The brain-targeted nasal drug delivery device comprises a body position fixator for keeping the body position of a user in such a position that a nasally delivered drug has access to a specific olfactory region of the upper nasal cavity; and an applicator for nasally delivering the drug to the user and targeting the drug at the brain in the case that the body position fixator keeps the user in the above-mentioned body position, wherein the drug delivery end of the applicator has a shape matching the nasal cavity of the user. In particular, the body position fixator comprises a head-bearing part (600) for bearing the head of a user and keeping the head in such a position that a nasally delivered drug has access to an olfactory region of the upper nasal cavity. The head-bearing part (600) comprises a headrest (610) for bearing the head of a user, a support frame (620) and a central axle (630) for rotatably supporting the headrest (610) on the support frame (620). By keeping a user in a specific drug delivery body position and controlling with a smart element, a nasally delivered drug can enter an olfactory region of the upper nasal cavity at a specific time, speed and quantity, thereby targeting and acting on the brain.
Inventors:
QIAN MINGXIN (CN)
HE RENYANG (CN)
SHI JUNWEI (CN)
HE RENYANG (CN)
SHI JUNWEI (CN)
Application Number:
PCT/CN2015/072648
Publication Date:
September 03, 2015
Filing Date:
February 10, 2015
Export Citation:
Assignee:
TONGLI BIOMEDICAL CO LTD (CN)
International Classes:
A61M31/00; A47C27/00; A61G15/00
Foreign References:
| CN2339073Y | 1999-09-22 | |||
| CN1861060A | 2006-11-15 | |||
| CN2377943Y | 2000-05-17 | |||
| CN101766523A | 2010-07-07 | |||
| CN201603040U | 2010-10-13 | |||
| CN202605169U | 2012-12-19 | |||
| JP2009125339A | 2009-06-11 | |||
| US20120266894A1 | 2012-10-25 |
Other References:
LIU, XINFENG ET AL.: "Intranasal Delivery of Insulin-Like Growth Factor-I to Central Nervous System via the Olfactory Pathway and Its Resulting in Protection Against Cerebral Infarct in Rats", CHINESE JOURNAL OF NEUROLOGY, vol. 37, no. 2, 30 April 2004 (2004-04-30), pages 149 - 153
LIU, XINFENG ET AL.: "Intranasal Delivery of Insulin-Like Growth Factor- to Central Nervous System via the Olfactory Pathway and Its Resulting in Protection Against Cerebral Infarct in Rats", CHINESE JOURNAL OF NEUROLOGY, vol. 37, no. 2, 30 April 2004 (2004-04-30), pages 149 - 153
LIU, XINFENG ET AL.: "Intranasal Delivery of Insulin-Like Growth Factor- to Central Nervous System via the Olfactory Pathway and Its Resulting in Protection Against Cerebral Infarct in Rats", CHINESE JOURNAL OF NEUROLOGY, vol. 37, no. 2, 30 April 2004 (2004-04-30), pages 149 - 153
Attorney, Agent or Firm:
BEIJING KINSCOM INTELLECTUAL PROPERTY AGENT CO., LTD. (CN)
北京金思港知识产权代理有限公司 (CN)
北京金思港知识产权代理有限公司 (CN)
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