Title:
CARBOHYDRATE MONOPHOSPHINES, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/073657
Kind Code:
A1
Abstract:
Provided by the present invention are carbohydrate monophosphines represented by general formula Ia, Ib, IIa or IIb, comprising mixtures represented by Ia and Ib having different phosphorus atom configurations, or mixtures represented by IIa and IIb having different phosphorus atom configurations, and a method for preparing same; the present invention describes borane adducts, oxides, sulfides or selenides of the carbohydrate monophosphines; in addition, further provided by the present invention is a palladium complex complexed with a carbohydrate monophosphine; a catalytic system composed of a carbohydrate monophosphine and palladium salt or a complex thereof, or a use of a palladium complex complexed with a carbohydrate monophosphine in catalyzing organic reactions is also a part of the present invention, in particular a use in catalyzing coupling reactions of (pseudo) haloaromatics to form new C-C or C-N bonds.
Inventors:
SHI JICHENG (CN)
ZHANG LIXUE (CN)
ZHANG LIXUE (CN)
Application Number:
PCT/CN2019/088461
Publication Date:
April 16, 2020
Filing Date:
May 27, 2019
Export Citation:
Assignee:
DONGGUAN STEPHEN CATALYST CO LTD (CN)
International Classes:
C07H23/00; C07B53/00
Foreign References:
| CN105968137A | 2016-09-28 | |||
| CN106674287A | 2017-05-17 |
Other References:
PARK, H. ET AL.: "Tunable Ligands for Asymmetric Catalysis: Readily Available Carbohydrate-Derived Diarylphosphinites Induce High Selectivity in the Hydrovinylation of Styrene Derivatives", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 124, no. 5, 15 December 2001 (2001-12-15), pages 734, XP055201912, ISSN: 0002-7863, DOI: 10.1021/ja0172013
SHI, JICHENG ET AL.: "Carbohydrate-Based Phosphines as Supporting Ligand for Palladium- Catalyzed Suzuki-Miyaura Cross-Coupling Reaction", TETRAHEDRON LETTERS, vol. 55, no. 18, 9 January 2014 (2014-01-09), pages 2905 - 2906, XP028638553, ISSN: 0040-4039
MENG, YEQING: "P-Stereogenic Phosphine Ligand derived from Carbohydrate and Composition and Structure Characterization of Transition Metal Complex Thereof", SCIENCE -ENGINEERING (A), CHINA MASTER S THESES FULL-TEXT DATABASE, 15 May 2012 (2012-05-15), pages 11 - 12, 17-23, 39; 45-47, ISSN: 1674-0246
SHI, JICHENG ET AL.: "Carbohydrate-Based Phosphines as Supporting Ligand for Palladium- Catalyzed Suzuki-Miyaura Cross-Coupling Reaction", TETRAHEDRON LETTERS, vol. 55, no. 18, 9 January 2014 (2014-01-09), pages 2905 - 2906, XP028638553, ISSN: 0040-4039
MENG, YEQING: "P-Stereogenic Phosphine Ligand derived from Carbohydrate and Composition and Structure Characterization of Transition Metal Complex Thereof", SCIENCE -ENGINEERING (A), CHINA MASTER S THESES FULL-TEXT DATABASE, 15 May 2012 (2012-05-15), pages 11 - 12, 17-23, 39; 45-47, ISSN: 1674-0246
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