Title:
CARBON-CARBON BOND FORMING REACTION
Document Type and Number:
WIPO Patent Application WO/2004/113258
Kind Code:
A1
Abstract:
A process for the production of compounds represented by the general formula (I), salts of the same, or solvate thereof from compounds represented by the general formulae (II) and (III), salts of the same, or solvates thereof, comprising the step represented by the reaction formula (A): [wherein R0 is lower alkyl or the like; R1 is lower alkyl or the like; R2 and R2’ are simultaneously hydrogen or the like; R3 is optionally substituted lower alkyl or the like; R4 is hydrogen or the like; X1 is halogeno; Y is hydroxyl or the like; Z1 is -CH=CH- or the like; Z2 is -CH=CH- or the like; m is an integer of 0 to 3; and n is an integer of 0 to 2] and characterized in that the reaction is conducted in a water-containing solvent in the presence of palladium-carbon.
Inventors:
UENAKA MASAAKI (JP)
KOSHIDA SHUHEI (JP)
KII MAKOTO (JP)
SHINOMOTO SHOJI (JP)
KOSHIDA SHUHEI (JP)
KII MAKOTO (JP)
SHINOMOTO SHOJI (JP)
Application Number:
PCT/JP2004/008523
Publication Date:
December 29, 2004
Filing Date:
June 17, 2004
Export Citation:
Assignee:
SHIONOGI & CO (JP)
UENAKA MASAAKI (JP)
KOSHIDA SHUHEI (JP)
KII MAKOTO (JP)
SHINOMOTO SHOJI (JP)
UENAKA MASAAKI (JP)
KOSHIDA SHUHEI (JP)
KII MAKOTO (JP)
SHINOMOTO SHOJI (JP)
International Classes:
C07C25/18; C07C303/40; C07C319/20; C07D333/34; C07C311/19; (IPC1-7): C07C17/263; C07C25/18; C07C41/30; C07C43/205; C07C45/68; C07C49/784; C07C51/353; C07C63/331; C07C63/70; C07C311/19; C07C311/29; C07C319/20; C07C323/62; C07C323/67; C07D333/08; C07D333/34
Domestic Patent References:
| WO1997027174A1 | 1997-07-31 |
Foreign References:
| US5756545A | 1998-05-26 | |||
| JP2003128608A | 2003-05-08 | |||
| JP2002537369A | 2002-11-05 |
Other References:
DICKERSON T.J. ET AL: "Catalysis of the photo-fries reaction: antibody-mediated stabilization of high energy states", J. AM. CHEM. SOC., vol. 125, no. 50, 2003, pages 15395 - 15401, XP002981859
CONLON D. ET AL: "Suzuki-Miyaura Cross-coupling with quasi-heterogeneous palladium", ADV. SYNTH. CATAL., vol. 345, no. 8, 2003, pages 931 - 935, XP002981860
SAKURAI H. ET AL: "Pd/C as reusable catalyst for the coupling reaction of halophenols and arylboronic acids in aquenous media", J. ORG. CHEM., vol. 67, no. 8, 2002, pages 2721 - 2722, XP002981861
MARCK G. ET AL: "Aryl couplings with heterogeneous palladium catalysts", TETRAHEDRON LETTERS, vol. 35, no. 20, 1994, pages 3277 - 3280, XP002161074
CONLON D. ET AL: "Suzuki-Miyaura Cross-coupling with quasi-heterogeneous palladium", ADV. SYNTH. CATAL., vol. 345, no. 8, 2003, pages 931 - 935, XP002981860
SAKURAI H. ET AL: "Pd/C as reusable catalyst for the coupling reaction of halophenols and arylboronic acids in aquenous media", J. ORG. CHEM., vol. 67, no. 8, 2002, pages 2721 - 2722, XP002981861
MARCK G. ET AL: "Aryl couplings with heterogeneous palladium catalysts", TETRAHEDRON LETTERS, vol. 35, no. 20, 1994, pages 3277 - 3280, XP002161074
Attorney, Agent or Firm:
Yamauchi, Hideaki (Ltd. Intellectual Property Department 12-4
Sagisu 5-chome, Fukushima-ku, Osaka-sh, Osaka 02, JP)
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