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Title:
CARBOPLATIN COMPLEX AND PHARMACEUTICAL PREPARATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/037059
Kind Code:
A1
Abstract:
The present invention relates to a carboplatin complex and a pharmaceutical preparation thereof. The carboplatin complex is a complex formed by combining carboplatin and 1,1-cyclobutanedicarboxylic acid by means of two hydrogen bonds, the two hydrogen bonds being formed between a carbonyl oxygen of a carboplatin molecule and a carboxy hydrogen of a 1,1-cyclobutanedicarboxylic acid molecule. Also provided is an application of the carboplatin complex in the preparation of antitumor drugs, antibacterial agents, antifungal drugs or antiviral drugs, and a quality control method for the carboplatin complex.

Inventors:
ZHENG JIANQIANG (CN)
Application Number:
PCT/CN2020/111393
Publication Date:
March 04, 2021
Filing Date:
August 26, 2020
Export Citation:
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Assignee:
ADVANCHL BIOTECHNOLOGY SERVICE CENTER SHANGHAI (CN)
International Classes:
C07F15/00; A61K31/282; A61P31/04; A61P31/20; A61P35/00; G01N23/20
Foreign References:
CN104122280A2014-10-29
CN109053808A2018-12-21
US6699901B12004-03-02
CN1311183A2001-09-05
CN104127402A2014-11-05
CN104693245A2015-06-10
Other References:
YANG XUQING , JIN XIANGLIN , SONG QINHUA , TANG KALUO , YANG ZHENYUN , ZHANG XIAOFENG , TANG YOUQI: "Structural Studies of Dicycloplatin—an Antitumor Supramolecule", SCIENCE CHINA, vol. 40, no. 5, 31 December 2010 (2010-12-31), pages 485 - 491, XP055786861
See also references of EP 4006043A4
Attorney, Agent or Firm:
LEADER PATENT & TRADEMARK FIRM (CN)
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