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Title:
CD38-BINDING AGENTS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/003050
Kind Code:
A3
Abstract:
Among other things, the present disclosure provides compounds comprising antibody binding moieties and CD38-binding targeting moieties. In some embodiments, provided compounds recruit various types of antibodies to diseased cells such as cancer cells, and induce immune activities to kill such cells. Provided technologies are useful for treating various diseases including cancer.

Inventors:
RASTELLI LUCA (US)
WELSCH MATTHEW ERNEST (US)
BUNIN ANNA (US)
ROSSI ANN MARIE K (US)
BERBASOVA TETYANA (US)
Application Number:
PCT/US2020/039466
Publication Date:
February 11, 2021
Filing Date:
June 24, 2020
Export Citation:
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Assignee:
KLEO PHARMACEUTICALS INC (US)
International Classes:
A61K38/10; A61K47/55; C07K16/30
Domestic Patent References:
WO2019023501A12019-01-31
WO2019002842A12019-01-03
WO2018222987A12018-12-06
Foreign References:
US20160346403A12016-12-01
Attorney, Agent or Firm:
LI, Xiaodong et al. (US)
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