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Title:
CLEAVABLE DNA-ENCODED LIBRARY
Document Type and Number:
WIPO Patent Application WO/2021/241528
Kind Code:
A1
Abstract:
The present invention pertains to a method for using a nucleic acid compound that contains a selectively cleavable site. Also, the present invention pertains to a DNA-encoded library, said DNA containing a selectively cleavable site, a composition for synthesizing the same, and a method for using the same.

Inventors:
NIWA MASATOSHI (JP)
TOKUGAWA MUNEFUMI (JP)
HAYASHIDA JUN (JP)
FUKANO HAJIME (JP)
Application Number:
PCT/JP2021/019685
Publication Date:
December 02, 2021
Filing Date:
May 24, 2021
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Assignee:
NISSAN CHEMICAL CORP (JP)
International Classes:
C07K17/00; C12N15/10; C12Q1/68
Domestic Patent References:
WO2019060857A12019-03-28
WO2005058479A22005-06-30
WO2018143475A12018-08-09
WO1993020243A11993-10-14
WO2004039825A22004-05-13
WO2005058479A22005-06-30
WO2010094036A12010-08-19
Other References:
NATURE CHEMICAL BIOLOGY, vol. 5, 2009, pages 647 - 654
ACS CHEMICAL BIOLOGY, vol. 13, 2018, pages 53 - 59
NATURE CHEMISTRY, vol. 10, 2018, pages 441 - 448
ANNUAL REVIEW OF BIOCHEMISTRY, vol. 87, 2018, pages 479 - 502
ACS COMBINATORIAL SCIENCE, vol. 22, 2020, pages 204 - 212
ARTIFICIAL DNA; PNA & XNA, vol. 5, 2014, pages e27896
CURRENT OPINION IN CHEMICAL BIOLOGY, vol. 26, 2015, pages 80 - 88
TAKASHI TAKAHASHITAKAYUKI DOI: "Journal of The Society of Synthetic Organic Chemistry", vol. 60, 2002, article "Combinatorial chemistry", pages: 426 - 433
NATURE METHOD, vol. 9, 2012, pages 72 - 74
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 115, 1993, pages 7128 - 7134
Attorney, Agent or Firm:
TSUKUNI & ASSOCIATES et al. (JP)
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