received by the International Bureau on 9 December 2019 (09.10.2019)

1. A combinatorial drug delivery device for delivering a predetermined selection of drug components, each of the drug components being contained in a drug vial, the device comprising:

a plurality of modules, wherein each of the modules includes:

a body having an interior volume formed to accommodate a drug vial;

a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula, terminating at a free end, and first and second ports, first and second openings being formed in the free end with first and second lumens extending therefrom, through the cannula and terminating at the first and second ports, respectively; and,

a base tray including:

a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules;

for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well;

passageways to connect the second inlet ports of certain wells with the first inlet ports of wells adjacent to the certain wells to permit fluid flow therebetween,

wherein, for each of the wells, the first and second inlet ports being configured to maintain the spike plate of the respective module in a stationary position with the module being inserted into the well.

2. A drug delivery device as in claim 1, further comprising a source of negative pressure to draw the drug components from the modules.

3. A drug delivery device as in claim 2, wherein the base tray includes a housing, the source of negative pressure being located in the housing.

4. A combinatorial drug delivery device for delivering a predetermined selection of drug components, each of the drug components being contained in a drug vial, the device comprising:

a plurality of modules, wherein each of the modules includes a body having an interior volume formed to accommodate a drug vial, a plurality of keying features being defined on the body; and, a base tray including a framework defining a plurality of wells bounded by upstanding walls, each of the wells formed to insertingly receive one of the modules, wherein tray keying features are defined on interior portions of the upstanding walls,

wherein, the keying features and the tray keying features are configured to permit insertion of the modules into predetermined wells to arrange the modules in a predetermined sequence along the base tray, with the keying features and the tray keying features restricting insertion of the modules into the wells which are not predetermined for the modules.

5. A drug delivery device as in claim 4, wherein the keying features include one or more ridges and channels.

6. A drug delivery device as in claim 5, wherein the tray keying features includes one or more ridges and channels.

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