Title:
COMPOSITE NANOPARTICLES
Document Type and Number:
WIPO Patent Application WO2005007284
Kind Code:
A3
Abstract:
The method of measuring the partition coefficient of a test molecule comprises incorporating the molecule in a composition of nanoparticles having a porous surface and a first solvent, wherein a second solvent has been absorbed into the porous surface, and said first solvent is immiscible with said second solvent, and then separating the nanoparticles and the first solvent. The amount of the molecule which remains in the first solvent is determined to enable calculation of the partition coefficient. The nanoparticles may have a magnetic core to allow easy separation.
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Inventors:
TSANG SHIK CHI (GB)
TAM KIN YIP (GB)
TAM KIN YIP (GB)
Application Number:
PCT/GB2004/003103
Publication Date:
June 16, 2005
Filing Date:
July 16, 2004
Export Citation:
Assignee:
UNIV READING (GB)
ASTRAZENECA AB (SE)
TSANG SHIK CHI (GB)
TAM KIN YIP (GB)
GAO XIN (GB)
ASTRAZENECA AB (SE)
TSANG SHIK CHI (GB)
TAM KIN YIP (GB)
GAO XIN (GB)
International Classes:
A61K9/51; A61K49/18; G01N13/00; A61K9/16; (IPC1-7): G01N13/00; A61K9/51; A61K49/18; B01J13/02
Domestic Patent References:
| WO2002080885A1 | 2002-10-17 | |||
| WO2003057359A2 | 2003-07-17 |
Foreign References:
| US6548264B1 | 2003-04-15 | |||
| US20020034827A1 | 2002-03-21 | |||
| GB1171795A | 1969-11-26 |
Other References:
HO T S ET AL: "Recovery, enrichment and selectivity in liquid-phase microextraction - Comparison with conventional liquid-liquid extraction", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 963, no. 1-2, 19 July 2002 (2002-07-19), pages 3 - 17, XP004368634, ISSN: 0021-9673
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