Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
COMPOSITION COMPRISING BILBERRY EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING SENSORINEURAL HEARING IMPAIRMENT
Document Type and Number:
WIPO Patent Application WO/2021/045569
Kind Code:
A1
Abstract:
The present invention relates to a composition comprising a bilberry extract as an active ingredient for preventing or treating sensorineural hearing impairment. The bilberry extract was found to exhibit effects of inhibiting the apoptosis of auditory cells in which sensorineural damage has been induced by neomycin and increasing a reduced number of hair cells in juvenile zebra fishes such that the composition comprising the bilberry extract as an active ingredient can be provided as a pharmaceutical composition and a health food for preventing or treating various hearing impairments induced by sensorineural damage.

Inventors:
PARK YOUNG-JOON (KR)
CHOI SOOK (KR)
Application Number:
PCT/KR2020/011961
Publication Date:
March 11, 2021
Filing Date:
September 04, 2020
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
IMDPHARM INC (KR)
International Classes:
A61K36/45; A23L33/105; A61P27/16
Foreign References:
JP2011037738A2011-02-24
US20090220592A12009-09-03
KR20180089207A2018-08-08
Other References:
KAPUSUZ ZELIHA; ÖZKIRIŞ MAHMUT; KALA MEHTAP; SAYDAM LEV: "Protective Role of Bilberry Extract Against Cisplatin Induced Ototoxicity in Rats", INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY, SPRINGER INDIA, INDIA, vol. 65, no. 4, 20 March 2013 (2013-03-20), India, pages 339 - 344, XP035359530, ISSN: 2231-3796, DOI: 10.1007/s12070-013-0642-x
DE RIVERA, C. ; SHUKITT-HALE, B. ; JOSEPH, J.A. ; MENDELSON, J.R.: "The effects of antioxidants in the senescent auditory cortex", NEUROBIOLOGY OF AGING, TARRYTOWN, NY, US, vol. 27, no. 7, 1 July 2006 (2006-07-01), US, pages 1035 - 1044, XP024993182, ISSN: 0197-4580, DOI: 10.1016/j.neurobiolaging.2005.05.003
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
Download PDF: