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Patent Searching and Data


Title:
COMPOSITION COMPRISING INDUCED EXOSOME FOR HAIR REGENERATION
Document Type and Number:
WIPO Patent Application WO/2020/071662
Kind Code:
A1
Abstract:
Disclosed is a method for preparation of exosomes having a hair regeneration effect, the method comprising the steps of: providing direct or indirect ultrasonic stimuli for cells; incubating a mixture of the cells and a medium for a predetermined period of time; and separating exosomes from the mixture, wherein the providing of direct ultrasonic stimuli refers to applying ultrasonic stimuli to a medium containing cells and the providing of indirect ultrasonic stimuli refers to applying ultrasonic stimuli to a cell-free medium which is then mixed with the cell. Such a method for preparation of exosomes allows the acquirement of exosomes having a hair regeneration effect at high yield within a short period of time through the simple process of ultrasonication from stem cells difficult to handle as well as somatic cells that can be easily obtained and maintained. The exosomes thus obtained also contain a large quantity of various factors. The exosomes and a composition containing same have increased numbers of various factors capable of inducing hair regeneration. Having a phospholipid-based membrane structure, the exosomes can easily penetrate into the scalp and deliver a material at a high rate to effectively induce hair regeneration. The exosomes are advantageously free of the adverse effects resulting from the use of synthetic medications.

Inventors:
LEE YONG SEUNG (KR)
Application Number:
PCT/KR2019/012134
Publication Date:
April 09, 2020
Filing Date:
September 19, 2019
Export Citation:
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Assignee:
STEMON INC (KR)
International Classes:
A61K8/98; A61Q5/00; C12N5/077; C12N13/00
Foreign References:
KR20170020245A2017-02-22
KR20170106149A2017-09-20
KR101894229B12018-09-04
KR20170044999A2017-04-26
KR20180015994A2018-02-14
KR101425653B12014-08-05
KR101781526B12017-09-26
KR101836029B12018-03-08
KR20170044999A2017-04-26
KR20180060317A2018-06-07
Other References:
See also references of EP 3861979A4
Attorney, Agent or Firm:
JIDAM IP LAW FIRM (KR)
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