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Title:
COMPOSITION FOR DIFFERENTIAL DIAGNOSIS OF ACANTHAMOEBA KERATITIS COMPRISING CHORISMATE MUTASE PROTEIN ANTIBODIES, AND ACANTHAMOEBA KERATITIS DIAGNOSIS KIT USING SAME
Document Type and Number:
WIPO Patent Application WO/2021/157907
Kind Code:
A1
Abstract:
The present invention relates to: a composition for differentially diagnosing acanthamoeba keratitis, the composition comprising chorismate mutase antibodies; and an acanthamoeba keratitis diagnosis kit using same. The composition comprising chorismate mutase antibodies according to the present invention causes an antigen-antibody reaction only specific to chorismate mutase secreted from acanthamoeba, thus making it possible to diagnose and identify the cause of acanthamoeba keratitis more rapidly and accurately than existing methods for diagnosing acanthamoeba keratitis. The composition is expected to be widely applicable to the production of acanthamoeba keratitis diagnosis kits, therapeutic agents, contact lens disinfecting agents, etc.

Inventors:
MOON EUN KYUNG (KR)
LEE HAE AHM (KR)
Application Number:
PCT/KR2021/000727
Publication Date:
August 12, 2021
Filing Date:
January 19, 2021
Export Citation:
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Assignee:
UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR)
International Classes:
G01N33/573; G01N33/569
Foreign References:
KR101308516B12013-09-17
KR101521409B12015-05-18
CN107501404A2017-12-22
KR20100044736A2010-04-30
Other References:
MOON EUN-KYUNG, CHOI HYUN-SEO, PARK SO-MIN, KONG HYUN-HEE, QUAN FU-SHI: "Comparison of Proteins Secreted into Extracellular Space of Pathogenic and Non-pathogenic Acanthamoeba castellanii", KOREAN JOURNAL OF PARASITOLOGY., SEOUL., KR, vol. 56, no. 6, 1 December 2018 (2018-12-01), KR, pages 553 - 558, XP055833578, ISSN: 0023-4001, DOI: 10.3347/kjp.2018.56.6.553
Attorney, Agent or Firm:
ISIS IP LAW LLC (KR)
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