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Patent Searching and Data


Title:
COMPOSITION FOR ENHANCING RADIATION SENSITIVITY CONTAINING AGELOXIME D AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2021/091107
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for enhancing radiation sensitivity containing ageloxime D as an active ingredient, and a composition for aiding anticancer treatment, wherein the ageloxime D increases the radiation sensitivity of cancer cells, and increases the expression of ATF4 in cancer cells, and thus can increase the effectiveness of anticancer treatments.

Inventors:
CHOI CHANG HOON (KR)
LEE YEON JU (KR)
PARK HEE CHUL (KR)
CHO YEON WOO (KR)
SON A RANG (KR)
LEE HYI SEUNG (KR)
Application Number:
PCT/KR2020/013927
Publication Date:
May 14, 2021
Filing Date:
October 13, 2020
Export Citation:
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Assignee:
KOREA INSTITUTE OF OCEAN SCIENCE & TECH (KR)
SAMSUNG LIFE PUBLIC WELFARE FOUNDATION (KR)
International Classes:
A61K31/506; A23L33/10; A61K41/00; A61P35/00
Other References:
HERTIANI TRIANA: "Isolation and Structure Elucidation of Bioactive Secondary Metabolites from Indonesian Marine Sponges", DISSERTATION, 1 January 2007 (2007-01-01), XP055809650, ISBN: 978-3-86727-327-5, Retrieved from the Internet
CHOI CHANGHOON, SON ARANG, LEE HYI-SEUNG, LEE YEON-JU, PARK HEE CHUL: "Radiosensitization by Marine Sponge Agelas sp. Extracts in Hepatocellular Carcinoma Cells with Autophagy Induction", SCIENTIFIC REPORTS, vol. 8, no. 1, 1 December 2018 (2018-12-01), pages 6317, XP055809656, DOI: 10.1038/s41598-018-24745-w
STOWE SEAN D., RICHARDS JUSTIN J., TUCKER ASHLEY T., THOMPSON RICHELE, MELANDER CHRISTIAN, CAVANAGH JOHN: "Anti-Biofilm Compounds Derived from Marine Sponges", MARINE DRUGS, vol. 9, no. 10, 1 January 2011 (2011-01-01), pages 2010 - 2035, XP055809658, DOI: 10.3390/md9102010
YANG FAN, HAMANN MARK T., ZOU YIKE, ZHANG MING-YU, GONG XIAO-BIN, XIAO JIAN-RU, CHEN WAN-SHENG, LIN HOU-WEN: "Antimicrobial Metabolites from the Paracel Islands Sponge Agelas mauritiana", JOURNAL OF NATURAL PRODUCTS, AMERICAN CHEMICAL SOCIETY, US, vol. 75, no. 4, 27 April 2012 (2012-04-27), US, pages 774 - 778, XP055809660, ISSN: 0163-3864, DOI: 10.1021/np2009016
YUNOVILSA PUTRA MASTERIA, JASWIR IRWANDI: "The Alkaloids from Indonesian Marine Sponges", JOURNAL OF OCEANOGRAPHY AND MARINE RESEARCH, vol. 02, no. 02, 1 January 2014 (2014-01-01), XP055809662, DOI: 10.4172/2332-2632.1000125
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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