Title:
COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING DEGENERATIVE BRAIN DISEASE, COMPRISING PERIOSTRACUM CICADAE EXTRACT
Document Type and Number:
WIPO Patent Application WO/2021/054637
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for use in the prevention or treatment of a degenerative brain disease or a composition for use in neuroprotection, comprising a Periostracum Cicadae extract. In addition, the present invention relates to a method for preventing or treating a degenerative brain disease, comprising the step of administering a Periostracum Cicadae extract to a patient with the degenerative brain disease. The Periostracum Cicadae extract of the present invention amplifies neurotrophic factors or dopamine by increasing the activity of Nurr1 proteome, and has a neuroprotection effect by inhibiting neuronal cell death or nerve inflammation, thereby ameliorating behavior disorders caused by a degenerative brain disease such as Parkinson's disease, and furthermore can be expected to have the effect of ameliorating lowering of concentration, ADHD, schizophrenia, depression, or manic depression resulting from a dopamine decrease.
Inventors:
PARK GUN HYUK (KR)
LIM HYE SUN (KR)
KIM JOONG SUN (KR)
MOON BYEONG CHEOL (KR)
CHOI GO YA (KR)
LEE JUN (KR)
RYU SEUNG MOK (KR)
LIM HYE SUN (KR)
KIM JOONG SUN (KR)
MOON BYEONG CHEOL (KR)
CHOI GO YA (KR)
LEE JUN (KR)
RYU SEUNG MOK (KR)
Application Number:
PCT/KR2020/011454
Publication Date:
March 25, 2021
Filing Date:
August 27, 2020
Export Citation:
Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
International Classes:
A61K35/64; A23L33/10; A61P25/28
Foreign References:
| KR20190102926A | 2019-09-04 | |||
| KR20160081870A | 2016-07-08 | |||
| KR20100134323A | 2010-12-23 |
Other References:
MOON, BYEONG HYEOK: "Molecular Mechanism in Inhibition of Neurocellular Death of Cryptotympana pulata Fabricus Water Extract", DONGGUK UNIVERSITY PH.D. THESIS, 1 January 2009 (2009-01-01), pages 1 - 48, XP009526908
KIM, SEOK RYEOL: "Effect of Neurotransmitters of White Rat Haemar Nerve Cells Grown by Cryptotympana pulata Fabrics Water Extract on the Expression of Receptors", PH.D. THESIS, 1 January 2009 (2009-01-01), pages 1 - 31, XP009526907
KIM, SEOK RYEOL: "Effect of Neurotransmitters of White Rat Haemar Nerve Cells Grown by Cryptotympana pulata Fabrics Water Extract on the Expression of Receptors", PH.D. THESIS, 1 January 2009 (2009-01-01), pages 1 - 31, XP009526907
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
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