Title:
COMPOSITION FOR PREVENTING OR TREATING CRANIAL NERVE SYSTEM DISEASES COMPRISING RITA OR DERIVATIVE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/112563
Kind Code:
A1
Abstract:
The prevent invention relates to a composition for preventing or treating cranial nerve system diseases, and by means of a compound according to one aspect, by inhibiting the death of adult hippocampal neural stem cells caused by stress and preserving the number of neural stem cells, the composition can be utilized in the prevention, amelioration, or treatment of mental diseases or neurodegenerative diseases, or in the prevention or amelioration of stress.
Inventors:
YU SEONG-WOON (KR)
JUNG SEONGHEE (KR)
JUNG SEONGHEE (KR)
Application Number:
PCT/KR2020/017476
Publication Date:
June 10, 2021
Filing Date:
December 02, 2020
Export Citation:
Assignee:
DAEGU GYEONGBUK INST SCIENCE & TECH (KR)
International Classes:
A61K31/381; A23L33/10; A61P25/18; A61P25/28
Foreign References:
| US20130331398A1 | 2013-12-12 | |||
| US20180200251A1 | 2018-07-19 | |||
| KR20190143833A | 2019-12-31 |
Other References:
L MICHEL ESPINOZA-FONSECA: "Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer", THEORETICAL BIOLOGY AND MEDICAL MODELLING, vol. 2, no. 1, 38, 20 September 2005 (2005-09-20), XP021010158, ISSN: 1742-4682, DOI: 10.1186/1742-4682-2-38
SYLVANIE SURGET, GÉRALDINE DESCAMPS, CAROLE BROSSEAU, VINCENT NORMANT, SOPHIE MAÏGA, PATRICIA GOMEZ-BOUGIE, NADÈGE GOUY-COLIN, CAT: "RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53 abnormalmyeloma cells independently of the p53 pathway", BMC CANCER, vol. 14, no. 1, 437, 14 June 2014 (2014-06-14), pages 1 - 13, XP021190205, ISSN: 1471-2407, DOI: 10.1186/1471-2407-14-437
SYLVANIE SURGET, GÉRALDINE DESCAMPS, CAROLE BROSSEAU, VINCENT NORMANT, SOPHIE MAÏGA, PATRICIA GOMEZ-BOUGIE, NADÈGE GOUY-COLIN, CAT: "RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53 abnormalmyeloma cells independently of the p53 pathway", BMC CANCER, vol. 14, no. 1, 437, 14 June 2014 (2014-06-14), pages 1 - 13, XP021190205, ISSN: 1471-2407, DOI: 10.1186/1471-2407-14-437
Attorney, Agent or Firm:
ISIS IP LAW LLC (KR)
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