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Title:
COMPOSITION FOR PREVENTING OR TREATING NEUROPATHIC PAIN, CONTAINING SYRINGARESINOL
Document Type and Number:
WIPO Patent Application WO/2021/060922
Kind Code:
A1
Abstract:
The present invention relates to a composition for preventing, ameliorating or treating neuropathic pain, comprising syringaresinol or a pharmaceutically acceptable salt thereof as an active ingredient. The composition of the present invention may be administered to a subject for which administration of an anticancer agent is scheduled or to which an anticancer agent has been administered, or to a subject which has suffered peripheral nerve damage, thereby preventing, ameliorating, or treating neuropathic pain.

Inventors:
KIM SUN KWANG (KR)
JANG DAE SIK (KR)
CHO IK HYUN (KR)
LEE ZEE HWAN (KR)
CHAE HYEONKYEONG (KR)
CHOI JONGHEE (KR)
Application Number:
PCT/KR2020/013091
Publication Date:
April 01, 2021
Filing Date:
September 25, 2020
Export Citation:
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Assignee:
UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR)
International Classes:
A61K31/34; A23L33/10; A61K45/06; A61P25/02; A61P25/04
Foreign References:
KR20040033983A2004-04-28
KR20180043184A2018-04-27
US9005678B12015-04-14
Other References:
CHANGMIN KIM , JI HWAN LEE , WOOJIN KIM , DONGXING LI , YANGSEOK KIM , KYUNGJIN LEE , SUN KWANG KIM: "The Suppressive Effects of Cinnamomi Cortex and Its Phytocompound Coumarin on Oxaliplatin-Induced Neuropathic Cold Allodynia in Rats", MOLECULES, vol. 21, no. 9, 20 September 2016 (2016-09-20), pages 1 - 12, XP055662118, DOI: 10.3390/molecules21091253
CHO YOUNG SEON; SONG WOO SEOK; YOON SANG HO; PARK KYEONG-YEOL; KIM MYOUNG-HWAN: "Syringaresinol suppresses excitatory synaptic transmission and picrotoxin-induced epileptic activity in the hippocampus through presynaptic mechanisms", NEUROPHARMACOLOGY, vol. 131, 7 December 2017 (2017-12-07), pages 68 - 82, XP085351327, ISSN: 0028-3908, DOI: 10.1016/j.neuropharm.2017.12.014
Attorney, Agent or Firm:
HANOL INTELLECTUAL PROPERTY AND LAW (KR)
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