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Title:
COMPOSITION FOR PREVENTING AND TREATING TAUOPATHIES
Document Type and Number:
WIPO Patent Application WO/2021/048195
Kind Code:
A3
Abstract:
This invention relates to the delivery of a composition, preferably a pharmaceutical composition, comprising D-pinitol, D-Chiro inositol or myo-inositol or any pharmaceutically acceptable salt thereof, for use in the treatment or prevention of disorders, diseases or conditions responsive to the stimulation of the ghrelin receptor in a subject in need thereof. In particular, for the treatment and/or prevention of disorders responsive to the positive modulation (stimulation) of the ghrelin receptor, such as diabetes, obesity-related disorders, and, most preferably, for treating or preventing age related conditions or diseases such as by promoting appetite, inhibiting insulin secretion and lowering insulin resistance, increasing growth hormone release, enhancing muscle vitality or fragility and treating or preventing sarcopenia by increasing net muscle mass, improving cognition (and/or treating or preventing diseases such as Azlheimer's disease, vascular dementia, Parkinson's Disease, and Huntington's disease) and treating or preventing age related hypertension.

Inventors:
RODRIGUEZ DE FONSECA FERNANDO (ES)
NAVARRO GALERA JUAN ANTONIO (ES)
BAIXERA LLANOS ELENA (ES)
DECARA DEL OLMO JUAN MANUEL (ES)
MEDINA VERA DINA (ES)
LOPEZ-GAMBERO ANTONIO JESÚS (ES)
SUAREZ PEREZ JUAN (ES)
SANJUA MERINO CARLOS (ES)
Application Number:
PCT/EP2020/075180
Publication Date:
April 29, 2021
Filing Date:
September 09, 2020
Export Citation:
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Assignee:
SERVICIO ANDALUZ DE SALUD (ES)
EURONUTRA S L (ES)
UNIV MALAGA (ES)
International Classes:
A61K31/05; A61K8/34; A61K31/075; A61P1/16; A61P3/06; A61P3/10; A61P5/06; A61P9/10; A61P9/12; A61P19/02; A61P19/10; A61P25/16; A61P25/28; A61P29/00; A61P35/00
Domestic Patent References:
WO2015134726A12015-09-11
Foreign References:
US20160151301A12016-06-02
US20060004096A12006-01-05
KR101671502B12016-11-02
Other References:
ORR MIRANDA E ET AL: "A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER, HAYWARTH, GB, vol. 38, no. 7, 25 April 2017 (2017-04-25), pages 637 - 648, XP085076281, ISSN: 0165-6147, DOI: 10.1016/J.TIPS.2017.03.011
Attorney, Agent or Firm:
HOFFMANN EITLE S.L.U. (ES)
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