Title:
COMPOSITION, FOR PREVENTING OR TREATING VALVULAR CALCIFICATION, COMPRISING NICLOSAMIDE
Document Type and Number:
WIPO Patent Application WO/2022/119152
Kind Code:
A1
Abstract:
The present invention provides a preventive, relieving or therapeutic pharmaceutical composition or food composition comprising niclosamide as an active ingredient.
Inventors:
OAK MIN HO (KR)
Application Number:
PCT/KR2021/015888
Publication Date:
June 09, 2022
Filing Date:
November 04, 2021
Export Citation:
Assignee:
UNIV NAT MOKPO IND ACAD COOP GROUP (KR)
International Classes:
A61K31/167; A23L33/10; A61P43/00
Foreign References:
| CN109464437A | 2019-03-15 | |||
| US20180042962A1 | 2018-02-15 |
Other References:
LIU FEI-LAN, CHEN CHUN-LIANG, LEE CHIA-CHUNG, WU CHENG-CHI, HSU TENG-HSU, TSAI CHANG-YOUH, HUANG HSU-SHAN, CHANG DEH-MING: "The Simultaneous Inhibitory Effect of Niclosamide on RANKL-Induced Osteoclast Formation and Osteoblast Differentiation", INTERNATIONAL JOURNAL OF MEDICAL SCIENCE, vol. 14, no. 9, 19 July 2017 (2017-07-19), AU , pages 840 - 852, XP055935763, ISSN: 1449-1907, DOI: 10.7150/ijms.19268
SUN YONG, CHANG HYUN, BYON KAIYU, YUAN JIANFENG, CHEN XIA, MAO JACK M, HEATH AMJAD, JAVED KUI, ZHANG PETER G, ANDERSON YABING, CHE: "Cellular Biology Smooth Muscle Cell–Specific Runx2 Deficiency Inhibits Vascular Calcification", CIRCULATION RESEARCH, vol. 111, no. 5, 17 August 2012 (2012-08-17), pages 543 - 552, XP055935765, DOI: 10.1161/CIRCRESAHA.112.267237
KHAN KASHIF, YU BIN, KIWAN CHRYSTINA, SHALAL YOUSIF, FILIMON SABIN, CIPRO MEGAN, SHUM-TIM DOMINIQUE, CECERE RENZO, SCHWERTANI ADEL: "The Role of Wnt/β-Catenin Pathway Mediators in Aortic Valve Stenosis", FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, vol. 8, 10 September 2020 (2020-09-10), pages 1 - 14, XP055935771, DOI: 10.3389/fcell.2020.00862
SUN YONG, CHANG HYUN, BYON KAIYU, YUAN JIANFENG, CHEN XIA, MAO JACK M, HEATH AMJAD, JAVED KUI, ZHANG PETER G, ANDERSON YABING, CHE: "Cellular Biology Smooth Muscle Cell–Specific Runx2 Deficiency Inhibits Vascular Calcification", CIRCULATION RESEARCH, vol. 111, no. 5, 17 August 2012 (2012-08-17), pages 543 - 552, XP055935765, DOI: 10.1161/CIRCRESAHA.112.267237
KHAN KASHIF, YU BIN, KIWAN CHRYSTINA, SHALAL YOUSIF, FILIMON SABIN, CIPRO MEGAN, SHUM-TIM DOMINIQUE, CECERE RENZO, SCHWERTANI ADEL: "The Role of Wnt/β-Catenin Pathway Mediators in Aortic Valve Stenosis", FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, vol. 8, 10 September 2020 (2020-09-10), pages 1 - 14, XP055935771, DOI: 10.3389/fcell.2020.00862
Attorney, Agent or Firm:
B&IP-JOOWON PATENT AND LAW FIRM (KR)
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