Title:
COMPOSITION USING NOVEL LACTOBACILLUS PLANTARUM KC3 STRAIN FOR PREVENTION OR TREATMENT OF IMMUNE IMPAIRMENT, RESPIRATORY INFLAMMATORY DISEASE, ALLERGY, AND ASTHMA AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/162282
Kind Code:
A1
Abstract:
The present invention relates to a composition comprising a novel lactic acid bacterium Lactobacillus plantarum KC3 (also referred to as "CKDB-KC3") as an active ingredient for alleviation of immune impairment and for prevention or treatment of a respiratory inflammatory disease. The novel strain Lactobacillus plantarum KC3 according to the present invention was found to have excellent activity of alleviating immune impairment and inhibiting a respiratory inflammatory disease as measured through animal experiments including an experiment for characteristics of the novel Lactobacillus plantarum KC3 strain (experimental example 1); an inhibitory effect of probiotics on the expression of bowel inflammatory cytokines (experimental example 2); a test for anti-inflammatory inhibitory effect on ear edema (experimental example 3); a protective effect on respiratory tract injury caused by air pollutants such as fine dust, etc. (experimental example 4, figure 1), etc. The composition was observed to be available as a pharmaceutical composition or health functional food for alleviation of immune impairment or for prevention and treatment of a respiratory inflammatory disease and as such, finds advantageous applications in a pharmaceutical composition, a health functional food, or a health supplemental food for alleviation of immune impairment and for prevention or treatment of a respiratory inflammatory disease.
Inventors:
SHIN HAN JAE (KR)
LEE MOON YONG (KR)
KIM YOUNG SIN (KR)
KIM DO HOON (KR)
LEE DONG HOON (KR)
LEE IN OCK (KR)
SEO MIN HO (KR)
HEO BO HYE (KR)
KIM WOO RI (KR)
KIM BYOUNG KOOK (KR)
CHOI IN SUK (KR)
LEE MOON YONG (KR)
KIM YOUNG SIN (KR)
KIM DO HOON (KR)
LEE DONG HOON (KR)
LEE IN OCK (KR)
SEO MIN HO (KR)
HEO BO HYE (KR)
KIM WOO RI (KR)
KIM BYOUNG KOOK (KR)
CHOI IN SUK (KR)
Application Number:
PCT/KR2021/001024
Publication Date:
August 19, 2021
Filing Date:
January 26, 2021
Export Citation:
Assignee:
KT & G CORP (KR)
CKD BIO CORP (KR)
CKD BIO CORP (KR)
International Classes:
A23L33/135; A61K35/747; A61P11/00; A61P37/00
Domestic Patent References:
| WO2016093450A1 | 2016-06-16 |
Foreign References:
| KR20130046897A | 2013-05-08 | |||
| KR101178217B1 | 2012-09-07 | |||
| KR20190034796A | 2019-04-03 | |||
| KR20190090409A | 2019-08-02 | |||
| KR102135879B1 | 2020-07-21 |
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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