Title:
COMPOUND ACTING AS ANTIBIOTICS
Document Type and Number:
WIPO Patent Application WO/2019/154412
Kind Code:
A1
Abstract:
Provided are a new antimicrobial agent compound as shown in the following general formula (I), a pharmaceutically acceptable salt thereof, an ester thereof, a prodrug thereof, a solvate thereof, a deuterated compound thereof, or a stereoisomer thereof. The compound of the present invention exhibits an excellent antibacterial activity, in particular an excellent antibacterial activity against gram bacteria. In the formula, the definition of each group is as set forth in the description.
Inventors:
HUANG ZHENHUA (CN)
LI LI (CN)
ZHANG MIN (CN)
LI LI (CN)
ZHANG MIN (CN)
Application Number:
PCT/CN2019/074771
Publication Date:
August 15, 2019
Filing Date:
February 11, 2019
Export Citation:
Assignee:
KBP BIOSCIENCES CO LTD (CN)
International Classes:
C07D307/16; A61K31/166; A61K31/4412; A61P31/04; C07D307/54; C07D333/24; C07D405/10
Domestic Patent References:
| WO2012031298A2 | 2012-03-08 | |||
| WO2004062601A2 | 2004-07-29 | |||
| WO2008154642A2 | 2008-12-18 | |||
| WO2011132712A1 | 2011-10-27 |
Foreign References:
| CN101765585A | 2010-06-30 | |||
| US20120258948A1 | 2012-10-11 | |||
| CN102267924A | 2011-12-07 | |||
| CN103003233A | 2013-03-27 | |||
| CN105777464A | 2016-07-20 |
Other References:
T. HIGUCHIV. STELLA, PRO-DRUGS AS NOVEL DELIVERY SYSTEMS, VOL. 14 OF THE A.C.S. SYMPOSIUM SERIES, vol. 14
"Bioreversible Carriers in Drug Design", 1987, AMERICAN PHARMACEUTICAL ASSOCIATION AND PERGAMON PRESS
"Pure Appl. Chem.", vol. 45, 1974, IUPAC, article "Recommendations for Section E, Fundamental Stereochemistry", pages: 13 - 30
FURNISSHANNAFORDSMITHTATCHELL: "Vogel's Textbook of Practical Organic Chemistry", 1989, LONGMAN SCIENTIFIC & TECHNICAL
"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically", vol. 26, 2006, NATIONAL COMMITTEE FOR CLINICAL LABORATORY STANDARDS, pages: M7 - A7
See also references of EP 3750881A4
"Bioreversible Carriers in Drug Design", 1987, AMERICAN PHARMACEUTICAL ASSOCIATION AND PERGAMON PRESS
"Pure Appl. Chem.", vol. 45, 1974, IUPAC, article "Recommendations for Section E, Fundamental Stereochemistry", pages: 13 - 30
FURNISSHANNAFORDSMITHTATCHELL: "Vogel's Textbook of Practical Organic Chemistry", 1989, LONGMAN SCIENTIFIC & TECHNICAL
"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically", vol. 26, 2006, NATIONAL COMMITTEE FOR CLINICAL LABORATORY STANDARDS, pages: M7 - A7
See also references of EP 3750881A4
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
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