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Title:
COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/063404
Kind Code:
A1
Abstract:
A biaryl compound. Specifically disclosed is a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.

Inventors:
WU LINGYUN (CN)
WANG CAILIN (CN)
XU XIONGBIN (CN)
TONG HAIJUN (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2020/119511
Publication Date:
April 08, 2021
Filing Date:
September 30, 2020
Export Citation:
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Assignee:
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D471/04; A61K31/395; A61K31/4353; A61P35/00; A61P37/00; C07D213/81; C07D513/04
Domestic Patent References:
WO2019192506A12019-10-10
WO2018119224A12018-06-28
WO2018119221A12018-06-28
WO2015033299A12015-03-12
WO2019087087A12019-05-09
WO2015034820A12015-03-12
WO2015160641A22015-10-22
WO2018119224A12018-06-28
WO2018119263A12018-06-28
WO2019160882A12019-08-22
Foreign References:
US20170174671A12017-06-22
CN109641885A2019-04-16
CN201910943193A2019-09-30
CN202010911882A2020-09-02
US20180305315A12018-10-25
Other References:
KATARZYNA GUZIK, TOMALA MARCIN, MUSZAK DAMIAN, KONIECZNY MAGDALENA, HEC ALEKSANDRA, BŁASZKIEWICZ URSZULA, PUSTUŁA MARCIN, BUTERA R: "Development of the Inhibitors That Target the PD-1/PD-L1 Interaction—A Brief Look at Progress on Small Molecules, Peptides and Macrocycles", MOLECULES, SPRINGER VERLAG, BERLIN, DE, vol. 24, no. 11, 1 June 2019 (2019-06-01), DE, pages 2071, XP055615035, ISSN: 1433-1373, DOI: 10.3390/molecules24112071
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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