Title:
COMPOUND COMPRISING MULTIVALENT SIALYLOLIGOSACCHARIDE RESIDUES, AND COMPOSITION FOR PREVENTING OR TREATING VIRAL INFECTION DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2020/040576
Kind Code:
A1
Abstract:
The present invention relates to a compound comprising multivalent sialyloligosaccharide residues, an optical isomer thereof or a pharmaceutically acceptable salt thereof, and a use of a composition containing same as an active ingredient for preventing or treating viral infection diseases. The present invention shows high hemagglutination inhibitory activity and virus neutralizing activity so as to have excellent antiviral activity, thereby being effectively usable as a composition for preventing or treating viral infection diseases.
Inventors:
WOO JIN SUK (KR)
KIM DAE HEE (KR)
LEE SANG MI (KR)
YOO SANG EUN (KR)
SEO WON MIN (KR)
JO EUN JI (KR)
YANG JI YOUNG (KR)
KIM LI LA (KR)
KIM DAE HEE (KR)
LEE SANG MI (KR)
YOO SANG EUN (KR)
SEO WON MIN (KR)
JO EUN JI (KR)
YANG JI YOUNG (KR)
KIM LI LA (KR)
Application Number:
PCT/KR2019/010716
Publication Date:
February 27, 2020
Filing Date:
August 22, 2019
Export Citation:
Assignee:
GENECHEM INC (KR)
International Classes:
C07H3/06; A23K20/163; A23K20/195
Foreign References:
| JP2009292789A | 2009-12-17 | |||
| KR20180020914A | 2018-02-28 |
Other References:
LANDERS, J. J.: "Prevention of influenza pneumonitis by sialic Acid- conjugated dendritic polymers", THE JOURNAL OF INFECTIOUS DISEASES, vol. 186, no. 9, 2002, pages 1222 - 1230, XP008020077, DOI: 10.1086/344316
BORGES, A. R.: "Multivalent dendrimeric compounds containing carbohydrates expressed on immune cells inhibit infection by primary isolates of HIV-1", VIROLOGY, vol. 408, no. 1, 2010, pages 80 - 88, XP027445973, DOI: 10.1016/j.virol.2010.09.004
NAGAO, M.: "Design of Glycopolymers Carrying Sialyl Oligosaccharides for Controlling the Interaction with the Influenza Virus", BIOMACROMOLECULES, 2017, pages 4385 - 4392, XP055687442
BORGES, A. R.: "Multivalent dendrimeric compounds containing carbohydrates expressed on immune cells inhibit infection by primary isolates of HIV-1", VIROLOGY, vol. 408, no. 1, 2010, pages 80 - 88, XP027445973, DOI: 10.1016/j.virol.2010.09.004
NAGAO, M.: "Design of Glycopolymers Carrying Sialyl Oligosaccharides for Controlling the Interaction with the Influenza Virus", BIOMACROMOLECULES, 2017, pages 4385 - 4392, XP055687442
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
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