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Title:
COMPOUND COMPRISING β-NICOTINAMIDE MONONUCLEOTIDE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF, AND METHOD FOR EVALUATING QUALITY AND METHOD FOR ASSESSING ENZYMATIC REACTIVITY OF SAID COMPOUND
Document Type and Number:
WIPO Patent Application WO/2021/192683
Kind Code:
A1
Abstract:
A compound comprising β-nicotinamide mononucleotide or a pharmacologically acceptable salt thereof, wherein the purity measured by HPLC is 95% or higher, and the reactivity to lactate dehydrogenase is 30 U or higher.

Inventors:
TAKETANI YUKIKO (JP)
MATSUKAWA HIROKAZU (JP)
SUNAHARA YOSHIKO (JP)
Application Number:
PCT/JP2021/004912
Publication Date:
September 30, 2021
Filing Date:
February 10, 2021
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Assignee:
ORIENTAL YEAST CO LTD (JP)
International Classes:
C07H19/048; C07K14/47
Domestic Patent References:
WO2018047715A12018-03-15
Foreign References:
JP2018534265A2018-11-22
JP2019525760A2019-09-12
JP2017504616A2017-02-09
Other References:
MCPHERSON ALEXANDER JR.: "Interaction of lactate dehydrogenase with its coenzyme, Nicotinamide-adenine dinucleotide", JOURNAL OF MOLECULAR BIOLOGY, vol. 51, no. 1, 1970, pages 39 - 46, XP024015008, DOI: 10.1016/0022-2836(70)90268-8
Attorney, Agent or Firm:
HIROTA, Koichi et al. (JP)
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