Title:
COMPOUND AND LABELED BIOMATERIAL USING SAME
Document Type and Number:
WIPO Patent Application WO/2023/032996
Kind Code:
A1
Abstract:
A compound which has at least two phosphor parts and a structure represented by general formula (I), and a labeled biomaterial. In the formula, X1 to X3 represent -O-, -S-, >NR1 or >CR2R3. R1 to R3 represent a hydrogen atom or a substituent. La and Lb represent a single bond or a divalent linking group. n is an integer greater than or equal to 2. However, at least one of R1 to R3, La and Lb which are included in the structure enclosed in ( )n includes -(L-O)gRE, and -(L-O)gRE in these groups is not bonded to at least one of a phosphor and a biomaterial. L represents an alkylene group, RE represents a hydrogen atom or an alkyl group, and g is 1 to 24. * represents an atomic bond.
Inventors:
SHIROKANE KENJI (JP)
YOSHIMITSU YUJI (JP)
HAMADA NAOKA (JP)
YOSHIMITSU YUJI (JP)
HAMADA NAOKA (JP)
Application Number:
PCT/JP2022/032641
Publication Date:
March 09, 2023
Filing Date:
August 30, 2022
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
C07K2/00; A61K47/54; A61K47/64; A61K49/00; C07K1/04; C07K1/107; C07K16/00; C09K11/06; G01N33/533
Domestic Patent References:
| WO2020172197A1 | 2020-08-27 | |||
| WO2020254654A1 | 2020-12-24 | |||
| WO2019230963A1 | 2019-12-05 | |||
| WO2021100814A1 | 2021-05-27 | |||
| WO2002026891A1 | 2002-04-04 | |||
| WO2018174078A1 | 2018-09-27 | |||
| WO2020175473A1 | 2020-09-03 |
Foreign References:
| JP2020530988A | 2020-11-05 | |||
| JP2018521308A | 2018-08-02 | |||
| JP2021020956A | 2021-02-18 | |||
| JP2020105187A | 2020-07-09 | |||
| JP2021011483A | 2021-02-04 | |||
| JP2019172826A | 2019-10-10 | |||
| JP2021141999A | 2021-09-24 | |||
| JP2022100573A | 2022-07-06 |
Other References:
KENDRA N. AVERY, ET AL: "Development of a High Affinity, Non-covalent Biologic to Add Functionality to Fabs", SCIENTIFIC REPORTS, vol. 5, no. 1, 1 July 2015 (2015-07-01), pages 1 - 5, XP055396433, DOI: 10.1038/srep07817
LUCAS C. D.REZENDEFLAVIOSILVA EMERY: "A Review of the Synthetic Strategies for the Development of BODIPY Dyes for Conjugation with Proteins", ORBITAL: THE ELECTRONIC JOURNAL OF CHEMISTRY, vol. 5, no. 1, 2013, pages 62 - 83, XP055974577
LUCAS C. D.REZENDEFLAVIOSILVA EMERY: "A Review of the Synthetic Strategies for the Development of BODIPY Dyes for Conjugation with Proteins", ORBITAL: THE ELECTRONIC JOURNAL OF CHEMISTRY, vol. 5, no. 1, 2013, pages 62 - 83, XP055974577
Attorney, Agent or Firm:
IIDA & PARTNERS et al. (JP)
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