Title:
COMPOUNDS AS CD73 INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2021/088901
Kind Code:
A1
Abstract:
Provided herein are the compounds that are inhibitors of CD73 and are useful in treating CD73-associated diseases or conditions. Compositions containing the compounds are also provided.
Inventors:
FENG JIANXIA (CN)
CHEN DIANJUN (CN)
KAYSER FRANK (US)
LIU CHONG (CN)
CHEN DIANJUN (CN)
KAYSER FRANK (US)
LIU CHONG (CN)
Application Number:
PCT/CN2020/126631
Publication Date:
May 14, 2021
Filing Date:
November 05, 2020
Export Citation:
Assignee:
BIOARDIS LLC (US)
FENG JIANXIA (CN)
FENG JIANXIA (CN)
International Classes:
C07H19/16; A61K31/662; A61K31/70; A61K31/7052; A61K31/7076; A61P35/00; C07H19/20; C07H19/207
Domestic Patent References:
| WO2020210970A1 | 2020-10-22 | |||
| WO2019173682A1 | 2019-09-12 | |||
| WO2017120508A1 | 2017-07-13 | |||
| WO2018183635A1 | 2018-10-04 | |||
| WO2018208980A1 | 2018-11-15 |
Other References:
BHATTARAI, S. ET AL.: "α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors.", J. MED. CHEM., vol. 58, no. 15, 6 July 2015 (2015-07-06), XP055337552, DOI: 10.1021/acs.jmedchem.5b00802
Attorney, Agent or Firm:
LIU, SHEN & ASSOCIATES (CN)
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