COMPOUNDS HAVING IMMUNOMODULATORY EFFECTS

Title:

COMPOUNDS HAVING IMMUNOMODULATORY EFFECTS

Document Type and Number:

WIPO Patent Application WO/1999/047534

Kind Code:

A1

Abstract:

Compounds represented by the structural formula: monosaccharide$m(7)Gal1$m(7)1'Cer(C24,sat.) which have immunomodulatory effects, in particular, a high immunopotentiating activity and a high antitumor activity.

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Inventors:

NUNOMURA SHIGEKI (JP)
OSAWA RYOICHI (JP)
ENDO AKIRA (JP)
SUDA ISAO (JP)

Application Number:

PCT/JP1999/001370

Publication Date:

September 23, 1999

Filing Date:

March 18, 1999

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Assignee:

NISSIN FOOD PRODUCTS LTD (JP)
NUNOMURA SHIGEKI (JP)
OSAWA RYOICHI (JP)
ENDO AKIRA (JP)
SUDA ISAO (JP)

International Classes:

C07H15/10; A61K31/70; A61K31/7028; A61P35/00; A61P37/00; A61P37/04; C07H15/04; (IPC1-7): C07H15/04; A61K31/70; C07H15/10

Domestic Patent References:

WO1994024142A1

1994-10-27

Foreign References:

JPH08283285A

1996-10-29

Other References:

MASAHIRO MORITA, ET AL.: "STRUCTURE-ACTIVITY RELATIONSHIP OF ALPHA-GALACTOSYLCERAMIDES AGAINST B16-BEARING MICE", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 38, 1 January 1995 (1995-01-01), US, pages 2176 - 2187, XP002919134, ISSN: 0022-2623, DOI: 10.1021/jm00012a018

Attorney, Agent or Firm:

Shobayashi, Masayuki (Minamiikebukuro 3-chome Toshima-ku Tokyo, JP)

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