COMPOUNDS AND METHOD FOR THE TREATMENT OF OVERACTIVE BLADDER

Title:

COMPOUNDS AND METHOD FOR THE TREATMENT OF OVERACTIVE BLADDER

Document Type and Number:

WIPO Patent Application WO2003037889

Kind Code:

A8

Abstract:

NK2R binding compounds in accord with structural diagram (I) useful for the treatment or prevention of OAB or UI in mammals, particularly humans are disclosed wherein in said compounds D, A, R<1>, R<3> and R<4> are as defined in the specification. Pharmaceutically-advantageous salts of the compounds, methods of use of the compounds, either alone or in combination with other pharmacological agents, and pharmaceutical compositions useful in practicing the methods of the invention are also disclosed.

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Inventors:

BIALECKI RUSSELL (US)
DANTZMAN CATHY (US)
HERZOG KEITH (US)

Application Number:

PCT/SE2002/001991

Publication Date:

May 06, 2004

Filing Date:

November 01, 2002

Export Citation:

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Assignee:

ASTRAZENECA AB (SE)
BIALECKI RUSSELL (US)
DANTZMAN CATHY (US)
HERZOG KEITH (US)

International Classes:

C07D211/76; A61K31/4545; A61K31/506; A61K31/513; A61K45/00; A61K45/06; A61P13/02; A61P13/10; C07D401/04; (IPC1-7): C07D401/04; A61K31/4545; A61P13/10

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