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Title:
COMPOUNDS AND PHARMACEUTICAL USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/213500
Kind Code:
A1
Abstract:
A compound of Formula (I) : (I) or a pharmaceutically acceptable salt thereof, in which Ring X is a 3 to 7 membered monocyclic ring, at least one of R1, R2, R3, and R4 is OR5 or CH2OR5 and the other R1, R2, R3, and R4 each independently are halogen, OH, OR5, CH2OR5, CO2H, OC=OR6, (C=O) R6, R6, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, H, or absent. Also provided herein are therapeutic uses of the compound of Formula (I).

Inventors:
TSAI GUOCHUAN EMIL (US)
MAO YI-WEN (CN)
LU LU-PING (CN)
CHANG WEI-HUA (CN)
HSIEH HAN-YI (CN)
HU JHE WEI (CN)
SHIH TSAI-MIAO (CN)
HUANG CHANHUI (CN)
Application Number:
PCT/CN2021/089301
Publication Date:
October 28, 2021
Filing Date:
April 23, 2021
Export Citation:
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Assignee:
SYNEURX INT TAIWAN CORP (CN)
International Classes:
C07C69/88; A61K31/216; A61K31/7024; A61P25/00; A61P31/14; C07C15/12; C07D309/02; C07H13/08
Domestic Patent References:
WO2019228408A12019-12-05
Foreign References:
CN1568968A2005-01-26
Other References:
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PARK JI-YOUNG; KIM JANG HOON; KWON JUNG MIN; KWON HYUNG-JUN; JEONG HYUNG JAE; KIM YOUNG MIN; KIM DOMAN; LEE WOO SONG; RYU YOUNG BA: "Dieckol, a SARS-CoV 3CLproinhibitor, isolated from the edible brown algaeEcklonia cava", BIOORGANIC, ELSEVIER, AMSTERDAM, NL, vol. 21, no. 13, 22 April 2013 (2013-04-22), AMSTERDAM, NL, pages 3730 - 3737, XP028558882, ISSN: 0968-0896, DOI: 10.1016/j.bmc.2013.04.026
Attorney, Agent or Firm:
LIU, SHEN & ASSOCIATES (CN)
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