Title:
COMPOUNDS USEFUL IN THE TREATMENT OF ANTHRAX
Document Type and Number:
WIPO Patent Application WO2003072015
Kind Code:
A3
Abstract:
This invention relates to a method of inhibiting growth of Bacillus anthracis, Bacillus cereus and/or Bacillus thuringiensis bacterial strains in a mammal comprising administration to a patient in need thereof a therapeutically effective amount of a carbapenem compound. In particular, this invention relates to a method of inhibiting growth of Bacillus anthracis, Bacillus cereus and/or Bacillus thuringiensis bacterial strains in a mammal using compounds having the structural formula (I) or a pharmaceutically acceptable salt, enantiomer, diastereomer or in vivo hydrolysable ester or mixture thereof. This invention further relates to the use of carbapenem compounds of formula I in the treatment of anthrax and other conditions which are related to an anthrax infection.
Inventors:
SCOLNICK EDWARD M (US)
Application Number:
PCT/US2002/035342
Publication Date:
April 22, 2004
Filing Date:
November 04, 2002
Export Citation:
Assignee:
MERCK & CO INC (US)
SCOLNICK EDWARD M (US)
SCOLNICK EDWARD M (US)
International Classes:
A61K31/41; A61K31/43; A61K31/431; C07D477/20; (IPC1-7): A01N43/00; A01N43/38; A01N43/64
Other References:
DATABASE HCAPLUS [online] XP002972698, Database accession no. 2002:223478
DATABASE HCAPLUS [online] XP002972699, Database accession no. 2002:217073
DATABASE HCAPLUS [online] XP002972699, Database accession no. 2002:217073
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