Title:
COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2014/173957
Kind Code:
A3
Abstract:
A compound of formula (I) wherein R is a C9-23 polyunsaturated alkenyl group; X is SO3R3, SO2R3, PO3R3, PO2R3, COCHal3, or COOR3; R1 and R2 are each independently H, a C1-6 a iky I group optionally substituted with OH, C6-10 aryl group optionally substituted with OH, C7-12 arylalkyl group optionally substituted with OH, COC1-6 alkyl group optionally substituted with OH, COC6-10 aryl group optionally substituted with OH, COC7-12 arylalkyl group optionally substituted with OH, or COCHaI3 group; hal is halide, preferably F; each R3 is independently H, C1-6 alkyl, C6-10 aryl, or C7-12arylalkyl; or a salt thereof.
Inventors:
SIMIC NEBOJŠA (NO)
JOHANSEN BERIT (NO)
IGIC ALEKSANDAR (RS)
JOHANSEN BERIT (NO)
IGIC ALEKSANDAR (RS)
Application Number:
PCT/EP2014/058248
Publication Date:
December 18, 2014
Filing Date:
April 23, 2014
Export Citation:
Assignee:
SIMIC NEBOJŠA (NO)
JOHANSEN BERIT (NO)
IGIC ALEKSANDAR (RS)
JOHANSEN BERIT (NO)
IGIC ALEKSANDAR (RS)
International Classes:
C07H15/04; A61K31/216; A61K31/351; A61K31/7032; A61K31/7034; A61P29/00; C07C69/734; C07D407/04; C07H15/18; C07H17/07
Domestic Patent References:
| WO2011039365A1 | 2011-04-07 |
Other References:
SYED BUKHARI ET AL: "Anti-inflammatory and antioxidant activities of Sclerochloa dura (Poaceae)", JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, no. 00, 21 January 2014 (2014-01-21), pages 3 - 3, XP055120426, ISSN: 0352-5139, DOI: 10.2298/JSC131202003B
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 28 May 2009 (2009-05-28), HUA, JIN MEI ET AL: "Inhibitory activity of ethanol extracts of Ailanthus altissima and luteolin-7-glucoside on phospholipase A2 activity", XP002725059, retrieved from STN Database accession no. 150:489348
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 28 May 2009 (2009-05-28), HUA, JIN MEI ET AL: "Inhibitory activity of ethanol extracts of Ailanthus altissima and luteolin-7-glucoside on phospholipase A2 activity", XP002725059, retrieved from STN Database accession no. 150:489348
Attorney, Agent or Firm:
CAMPBELL, Neil (St Bride's House10 Salisbury Square, London EC4Y 8JD, GB)
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