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Title:
CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME
Document Type and Number:
WIPO Patent Application WO/2016/024605
Kind Code:
A1
Abstract:
 The present invention addresses the problem of providing a crystal of a cyclic phosphonic acid sodium salt (2ccPA) having high purity and excellent storage stability, and a method for manufacturing the same. The present invention provides a crystal of a cyclic phosphonic acid sodium salt (2ccPA) represented by formula (1).

Inventors:
YUASA HIROAKI (JP)
OKAZAKI HIROKI (JP)
Application Number:
PCT/JP2015/072825
Publication Date:
February 18, 2016
Filing Date:
August 12, 2015
Export Citation:
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Assignee:
OTSUKA CHEMICAL CO LTD (JP)
International Classes:
C07F9/6574; A61K31/665
Domestic Patent References:
WO2013069404A12013-05-16
Foreign References:
JPH06228169A1994-08-16
Other References:
EMI NOZAKI ET AL.: "Synthesis of enantiopure 2- carba-cyclic phosphatidic acid and effects of its chirality on biological functions", BIOCHIMICA ET BIOPHYSICA ACTA , MOLECULAR AND CELL BIOLOQY OF LIPIDS, vol. 1811, 2011, pages 271 - 277, XP028171396, DOI: doi:10.1016/j.bbalip.2011.01.003
AYAKO UCHIYAMA ET AL.: "Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid", BIOCHIMICA ET BIOPHYSICA ACTA , MOLECULAR AND CELL BIOLOGY OF LIPIDS, vol. 1771, 2007, pages 103 - 112, XP005829095
NORIAKI HIRAYAMA ET AL., KAGOBUTSU KESSHO SAKUSEI HANDBOOK, 2008, pages 17 - 23, XP008183763
See also references of EP 3181573A4
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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