Title:
CRYSTAL FORM G OF BULLEYACONITINE A, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/186963
Kind Code:
A1
Abstract:
Crystal form G of bulleyaconitine A and a preparation method therefor. Crystal form G of bulleyaconitine A was prepared by adding bulleyaconitine A to a mixed solution of methanoic acid and n-heptane and dissolving, stirring at a low temperature, evaporating a solvent at a high temperature, and leaving the resultant to stand at room temperature to obtain a solid. After characterization by XRD, the solid was determined to have crystal form G.
Inventors:
WU QIONGFEN (CN)
LI BIAO (CN)
LI BIAO (CN)
Application Number:
PCT/CN2020/076157
Publication Date:
September 24, 2020
Filing Date:
February 21, 2020
Export Citation:
Assignee:
YUNNAN HAOPY PHARMACEUTICALS LTD (CN)
International Classes:
C07D221/22; A61P19/02; A61P19/08; A61P21/00; A61P29/00
Foreign References:
| CN109776417A | 2019-05-21 | |||
| CN104326981A | 2015-02-04 | |||
| CN102775349A | 2012-11-14 | |||
| CN106008344A | 2016-10-12 | |||
| CN102924376B | 2014-10-29 | |||
| CN101830849B | 2012-04-18 | |||
| CN101555227A | 2009-10-14 | |||
| CN107245054A | 2017-10-13 |
Other References:
YUAN, MEI ET AL.: "Non-official translation: Chemical Constituents of Aconitum Bulleyanum", JOURNAL OF CHINESE MEDICINAL MATERIALS, vol. 36, no. 6, 30 June 2013 (2013-06-30), ISSN: 1001-4454
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
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