CRYSTAL FORM OF HYPOXIA-INDUCIBLE FACTOR-PROLYL HYDROXYLASE INHIBITOR

Title:

CRYSTAL FORM OF HYPOXIA-INDUCIBLE FACTOR-PROLYL HYDROXYLASE INHIBITOR

Document Type and Number:

WIPO Patent Application WO/2021/077994

Kind Code:

A1

Abstract:

Disclosed are a new crystal form of compound I and a preparation method therefor, a pharmaceutical composition comprising the crystal form, and the use of the crystal form in the preparation of hypoxia-inducible factor-prolyl hydroxylase inhibitor drugs and drugs for treating conditions mediated by hypoxia-inducible factors. The crystal form of compound I has one or more improved properties compared with that in the prior art, and is of great value to the optimization and development of such drugs in the future.

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Inventors:

CHEN MINHUA (CN)
WU KELIN (CN)
SHI JIAMING (CN)

Application Number:

PCT/CN2020/118386

Publication Date:

April 29, 2021

Filing Date:

September 28, 2020

Export Citation:

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Assignee:

CRYSTAL PHARMACEUTICAL SUZHOU CO LTD (CN)

International Classes:

C07D217/26; A61K31/472; A61P7/06; A61P13/12

Domestic Patent References:

WO2019030711A1	2019-02-14
WO2019042485A1	2019-03-07
WO2014014835A2	2014-01-23
WO2019030711A1	2019-02-14
WO2019042641A1	2019-03-07
WO2019042485A1	2019-03-07
WO2013013609A1	2013-01-31

Foreign References:

CN109369525A	2019-02-22
IN201641043301A	2018-06-22
CN104684897A	2015-06-03
CN104024227A	2014-09-03
CN106187888A	2016-12-07
CN109369525A	2019-02-22
CN111320583A	2020-06-23
IN201641043301A	2018-06-22
IN201841027602A
CN110218184A	2019-09-10
IN201741007950A
IN201641016266A

Other References: