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Patent Searching and Data


Title:
CRYSTALLINE 3',5'-CYCLIC DIGUANYLIC ACID
Document Type and Number:
WIPO Patent Application WO/2015/133411
Kind Code:
A1
Abstract:
The purpose of the present invention is to search for: a free acid crystal of 3',5'-cyclic diguanylic acid, which does not contain a salt with a metal such as cobalt and magnesium; and a method for producing the crystal in a simple manner and in a large quantity. A 3',5'-cyclic diguanylic acid crystal can be produced in a simple manner and in a large quantity by a production method comprising a step of adding an acid to an aqueous 3',5'-cyclic diguanylic acid solution to decrease the pH value of the solution to 1 to 3. The crystal is in the form of a free acid crystal which does not contain a salt with a metal such as cobalt and magnesium.

Inventors:
TANAKA HISAKI (JP)
ISHIGE KAZUYA (JP)
Application Number:
PCT/JP2015/055975
Publication Date:
September 11, 2015
Filing Date:
February 27, 2015
Export Citation:
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Assignee:
YAMASA CORP (JP)
International Classes:
C07H19/213
Domestic Patent References:
WO2010101526A12010-09-10
Foreign References:
Other References:
YAN H ET AL., NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS, vol. 26, 2007, pages 189 - 204, XP 055331730
KAZUYA ISHIGE, BIOSCIENCE & INDUSTRY, vol. 70, no. 6, 1 November 2012 (2012-11-01), pages 466 - 467, XP008174493
NORIAKI HIRAYAMA, YUKI KAGOBUTSU KESSHO SAKUSEI HANDBOOK, 2008, pages 17 - 23 , 37 to 40, 45 to 51, 57 to 65, XP008183763
See also references of EP 3121188A4
Attorney, Agent or Firm:
SK INTELLECTUAL PROPERTY LAW FIRM et al. (JP)
SK patent business corporation (JP)
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