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Title:
CULTURE MEDIUM, CULTURE METHOD AND USE OF PRIMARY OVARIAN CANCER CELLS
Document Type and Number:
WIPO Patent Application WO/2023/060677
Kind Code:
A1
Abstract:
A culture medium and culture method for primary ovarian cancer cells. The culture medium contains an MST1/2 kinase inhibitor; sodium pyruvate; forskolin; epidermal growth factor; gastrin; fibroblast growth factor 7; nicotinamide; SB431542; and fetal bovine serum. Compared with an existing culture method, in-vitro culture using the culture medium has a higher expansion efficiency; and the culture of primary ovarian cancer cells with the culture medium can maintain the morphological structure and pathological characteristics of primary tissue and improve the success rate and survival rate in the culture of primary ovarian cancer cells.

Inventors:
LIU QING SONG (CN)
HE YU YING (CN)
HUANG TAO (CN)
CHEN CHENG (CN)
Application Number:
PCT/CN2021/128998
Publication Date:
April 20, 2023
Filing Date:
November 05, 2021
Export Citation:
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Assignee:
PRECEDO PHARMACEUTICALS CO LTD (CN)
International Classes:
C12Q1/02; C12N5/09
Foreign References:
CN113528444A2021-10-22
CN113528425A2021-10-22
CN111607568A2020-09-01
CN111039944A2020-04-21
CN111621479A2020-09-04
Other References:
WANG HAINA, WANG RUI, HUANG DAN, LI SIHAN, GAO BEIBEI, KANG ZHIJIE, TANG BO, XIE JIAJUN, YAN FANZHI, LIANG RUI, LI HUA, YAN JINSON: "Homoharringtonine Exerts Anti-tumor Effects in Hepatocellular Carcinoma Through Activation of the Hippo Pathway", FRONTIERS IN PHARMACOLOGY, vol. 12, XP093056583, DOI: 10.3389/fphar.2021.592071
Attorney, Agent or Firm:
SHANGCHENG & PARTNERS (CN)
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